195195-95-0

Basic information

• Product Name: (S)-2-(hydroxydiphenylmethyl)-1-(3'-pyridylmethyl)pyrrolidine
• Synonyms: (S)-2-(hydroxydiphenylmethyl)-1-(3'-pyridylmethyl)pyrrolidine
• CAS NO: 195195-95-0
• Molecular Weight: 344.456
• Mol File: 195195-95-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-(hydroxydiphenylmethyl)-1-(3'-pyridylmethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(hydroxydiphenylmethyl)-1-(3'-pyridylmethyl)pyrrolidine(195195-95-0)
• EPA Substance Registry System: (S)-2-(hydroxydiphenylmethyl)-1-(3'-pyridylmethyl)pyrrolidine(195195-95-0)

Safety Data

• Hazardous Substances Data: 195195-95-0(Hazardous Substances Data)

Upstream product

• 3099-31-8 nicotinyl chloride 
• 212392-64-8 (S)-1-Pyridin-3-ylmethyl-pyrrolidine-2-carboxylic acid methyl ester 
• 22348-32-9 (S)-diphenylprolinol 

Relevant articles and documents

Asymmetric Cyanosilylation of Ketones Catalyzed by Bifunctional Chiral N-Oxide Titanium Complex Catalysts

A new bifunctional catalytic system based on chiral N-oxide titanium complexes has been used for the asymmetric cyanosilylation of ketones. Screening of a variety of chiral N-oxide metal complexes resulted in (1R,2S)-1-(2'-pyridylmethyl)-2-(diphenylhydroxymethyl)pyrrolidine N-oxide titanium complex, which gave O-TMS cyanohydrins in good yields with enantiometric excesses of up to 69 percent. A catalytic cycle based on experimental phenomena and studies was proposed to explain the origin of the asymmetric induction.