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4-DIPHENYLACETOXY-N-METHYLPIPERIDINE METHIODIDE, also known as 4-DAMP, is a quaternary ammonium salt derived from the combination of 4-diphenylacetoxy-N-methylpiperidine and iodomethane. It is a potent muscarinic M3 receptor antagonist, which plays a significant role in various applications across different industries.

1952-15-4

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1952-15-4 Usage

Uses

Used in Pharmaceutical Industry:
4-DIPHENYLACETOXY-N-METHYLPIPERIDINE METHIODIDE is used as a muscarinic M3 receptor antagonist for its ability to block the action of acetylcholine on the M3 receptor. This property makes it a valuable compound in the development of drugs targeting conditions related to the overactivation of the muscarinic M3 receptor, such as asthma, chronic obstructive pulmonary disease (COPD), and overactive bladder.
Used in Research Applications:
In the field of scientific research, 4-DIPHENYLACETOXY-N-METHYLPIPERIDINE METHIODIDE is used as a research tool for studying the role of muscarinic M3 receptors in various physiological processes and disease states. Its antagonistic action on the M3 receptor helps researchers understand the underlying mechanisms and potential therapeutic targets for a range of conditions.
Used in Drug Development:
4-DIPHENYLACETOXY-N-METHYLPIPERIDINE METHIODIDE is utilized in the development of new drugs targeting the muscarinic M3 receptor. Its antagonistic properties make it a promising candidate for the creation of novel therapeutic agents that can effectively manage conditions associated with the overactivation of this receptor.

Biological Activity

Antagonist at the M 3 cholinergic receptor. [ 3 H]-4-DAMP selectively labels M 1 and M 3 receptors.

Biochem/physiol Actions

4-DAMP is a M3 preferring cholinergic receptor antagonist.

Check Digit Verification of cas no

The CAS Registry Mumber 1952-15-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,5 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1952-15:
(6*1)+(5*9)+(4*5)+(3*2)+(2*1)+(1*5)=84
84 % 10 = 4
So 1952-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1

1952-15-4 Well-known Company Product Price

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  • (Code)Product description
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  • Sigma

  • (SML0255)  4-DAMP  ≥98% (HPLC)

  • 1952-15-4

  • SML0255-10MG

  • 666.90CNY

  • Detail
  • Sigma

  • (SML0255)  4-DAMP  ≥98% (HPLC)

  • 1952-15-4

  • SML0255-50MG

  • 2,165.67CNY

  • Detail

1952-15-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate,iodide

1.2 Other means of identification

Product number -
Other names 4-diphenylacetoxy-1,1-dimethyl-piperidinium,iodide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1952-15-4 SDS

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