1952-84-7Relevant academic research and scientific papers
Synthesis and Biological Evaluation of New Eugenol Mannich Bases as Promising Antifungal Agents
Abr?o, Pedro Henrique O.,Pizi, Rafael B.,De Souza, Thiago B.,Silva, Naiara C.,Fregnan, Antonio M.,Silva, Fernanda N.,Coelho, Luiz Felipe L.,Malaquias, Luiz Cosme C.,Dias, Amanda Latercia T.,Dias, Danielle F.,Veloso, Marcia P.,Carvalho, Diogo T.
, p. 459 - 465 (2015)
New Mannich base-type eugenol derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 4-allyl-2-methoxy-6-(morpholin-4-ylmethyl) phenyl benzoate (7) and 4-{5-allyl-2-[(
Design, synthesis, biological evaluation and molecular modeling studies of novel eugenol esters as leishmanicidal agents
Coelho, Camila M.,Dos Santos, Thiago,Freitas, Poliany G.,Nunes, Juliana B.,Marques, Marcos J.,Padovani, Camila G. D.,Júdice, Wagner A. S.,Camps, Ihosvany,Da Silveira, Nelson J. F.,Carvalho, Diogo T.,Veloso, Marcia P.
, p. 715 - 728 (2018/02/07)
Leishmaniasis is a neglected pathology with a high incidence worldwide, and is a governmental health issue due to the increased morbidity and mortality associated with the disease and a scarce therapeutic arsenal. Cysteine proteases have been investigated
