195243-75-5Relevant academic research and scientific papers
Heterocyclic rimantadine analogues with antiviral activity
Stamatiou, George,Foscolos, George B.,Fytas, George,Kolocouris, Antonios,Kolocouris, Nicolas,Pannecouque, Christophe,Witvrouw, Myriam,Padalko, Elizaveta,Neyts, Johan,Clercq, Erik De
, p. 5485 - 5492 (2003)
2-(1-Adamantyl)pyrrolidines 6, 7, 2-(1-adamantyl)piperidines 10, 12a-c, 15a,b and 2-(1-adamantyl)hexahydroazepines 19, 21, 22 were synthesized and tested for their antiviral activity against influenza A, B viruses and the human immunodeficiency virus type
Synthesis and anti-HIV activity of some new aminoadamantane heterocycles
Fytas,Stamatiou,Foscolos,Kolocouris,Kolocouris,Witvrouw,Pannecouque,De Clercq
, p. 1887 - 1890 (1997)
A new class of aminoadamantane heterocycles has been synthesized and examined for anti-HIV activity. Three compounds proved to be active against the replication of HIV-1 in MT-4 cells with an EC50 ranging from 3.6 to 75.2 μM. No activity was no
