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NSC 42834, also known as 2-phenyl-4-quinolinecarboxylic acid, is a chemical compound with demonstrated potential antitumor and anticancer properties. It has been recognized for its ability to inhibit the growth of various cancer cell lines, such as breast, lung, and colon cancer cells. NSC 42834 operates by disrupting the cell cycle and promoting cell death in cancer cells, positioning it as a promising candidate for the development of innovative cancer treatments. Further investigation is essential to elucidate its mechanisms of action and to assess its full potential as a therapeutic agent.

195371-52-9

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Basic information
1. Product Name: NSC 42834
2. Synonyms: JAK2 Inhibitor V, Z3;NSC 42834;1-Butanone, 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-;2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone;NSC 42834 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone;NSC 42834 Z 3 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone;Z3(NSC 42834);JAK2 Inhibitor V, Z3, >=98%
3. CAS NO:195371-52-9
4. Molecular Formula: C23H24N2O
5. Molecular Weight: 344.44946
6. EINECS: N/A
7. Product Categories: Inhibitors
8. Mol File: 195371-52-9.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: NSC 42834(CAS DataBase Reference)
10. NIST Chemistry Reference: NSC 42834(195371-52-9)
11. EPA Substance Registry System: NSC 42834(195371-52-9)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 195371-52-9(Hazardous Substances Data)

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195371-52-9 Usage

Uses

Used in Pharmaceutical Industry:
NSC 42834 is used as a potential anticancer agent for its ability to inhibit the growth of various cancer cell lines. It is particularly effective against breast, lung, and colon cancer cells, making it a valuable compound for the development of new cancer treatments.
NSC 42834 is used as a cell cycle disruptor for its mechanism of action that involves interfering with the cell cycle progression in cancer cells, thereby inducing cell death and potentially offering a new approach to combat cancer.
NSC 42834 is also used in research settings to study the mechanisms of action related to its antitumor properties, with the aim of understanding its full therapeutic potential and identifying ways to enhance its efficacy in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 195371-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,3,7 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 195371-52:
(8*1)+(7*9)+(6*5)+(5*3)+(4*7)+(3*1)+(2*5)+(1*2)=159
159 % 10 = 9
So 195371-52-9 is a valid CAS Registry Number.

195371-52-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-methyl-1-phenyl-4-pyridin-2-yl-2-(2-pyridin-2-ylethyl)butan-1-one

1.2 Other means of identification

Product number	-
Other names	2-methyl-1-phenyl-4-(pyridin-2-yl)-2-[2-(pyridin-2-yl)ethyl]butan-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:195371-52-9 SDS

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