195375-51-0

Downstream Products

• 1421632-78-1 N₂-isobutyryl-5'-O-tert-butyldimethylsilyl-3'-S-benzoyl-2'-deoxy-3'-thioguanosine 
• 1421632-82-7 N₂-isobutyryl-5'-O-dimethoxytrityl-2'-deoxy-3'-thio-guanosine-3'-S-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite 
• 1421632-81-6 N₂-isobutyryl-5'-O-dimethoxytrityl-2'-deoxy-3'-thioguanosine 
• 934980-57-1 N²-isobutyryl-5'-(4,4'-dimethoxytrityl)-3'-S-benzoyl-2',3'-dideoxy-3'-thioguanosine 
• 934980-59-3 N²-isobutyryl-3'-S-benzoyl-2',3'-dideoxy-3'-thioguanosine 
• 195375-56-5 Diphenyl-carbamic acid 9-[(2R,4S,5S)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-(trityl-amino)-tetrahydro-furan-2-yl]-2-isobutyrylamino-9H-purin-6-yl ester 
• 195375-57-6 Diphenyl-carbamic acid 9-[(2R,4S,5S)-5-hydroxymethyl-4-(trityl-amino)-tetrahydro-furan-2-yl]-2-isobutyrylamino-9H-purin-6-yl ester 
• 195375-54-3 5'-O-(tert-butyldimethylsilyl)-N²-isobutyryl-3'-tritylamino-2',3'-dideoxyguanosine 
• 195375-55-4 N²-isobutyryl-3'-NH-trityl-2',3'-dideoxyguanosine 

Relevant academic research and scientific papers

Potential application of thymidylate kinase in nucleoside analogue activation in Plasmodium falciparum

Plasmodium falciparum thymidylate kinase (PfTMPK) shows a broad range of substrate tolerance when compared to the corresponding human enzyme. Besides 2′-deoxythymidine monophosphate (dTMP), PfTMPK can phosphorylate 3′-azido-2′,3′-dideoxythymidine monophos