195626-05-2Relevant articles and documents
Stereospecific Allylation of a Serine-derived Zinc/Copper Reagent. Synthesis of Substituted Pipecolic Acid Derivatives
Jackson, Richard F.W.,Turner, Debra,Block, Michael H.
, p. 789 - 790 (1997)
Serine-derived zinc/copper reagents 1 and 2 add to enantiomerically pure (η3-allyl)iron tetracarbonyl salts in fair to good yield in a stereospecific fashion. The vinylsulfones 10-12 can be converted into 4-methylpipecolic acid derivatives 19-21 in a two-step process comprising epoxidation and Zn/TMSCl mediated cyclisation.