Cas 195727-65-2,4(S)-[(benzyloxycarbonyl)amino]-2,2-difluoro-3(R)-hydroxy-N,5-dimethylhexanamide

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Check Digit Verification of cas no

The CAS Registry Mumber 195727-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,7,2 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 195727-65:
(8*1)+(7*9)+(6*5)+(5*7)+(4*2)+(3*7)+(2*6)+(1*5)=182
182 % 10 = 2
So 195727-65-2 is a valid CAS Registry Number.

195727-65-2Upstream product

74-89-5 methylamine

195727-65-2Downstream Products

195727-65-2Relevant articles and documents

Orally active trifluoromethyl ketone inhibitors of human leukocyte elastase

Veale, Chris A.,Bernstein, Peter R.,Bohnert, Claudia M.,Brown, Frederick J.,Bryant, Craig,Damewood Jr., James R.,Earley, Roger,Feeney, Scott W.,Edwards, Philip D.,Gomes, Bruce,Hulsizer, James M.,Kosmider, Ben J.,Krell, Robert D.,Moore, Gary,Salcedo, Theodora W.,Shaw, Andrew,Silberstein, David S.,Steelman, Gary B.,Stein, Mark,Strimpler, Anne,Thomas, Roy M.,Vacek, Edward P.,Williams, Joseph C.,Wolanin, Donald J.,Woolson, Sheila

, p. 3173 - 3181 (1997)

This paper describes the development a series of peptidyl trifluoromethyl ketone inhibitors of human leukocyte elastase which are found to have excellent pharmacological profiles. Methods have been developed that allow for the synthesis of these inhibitor

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195727-65-2