195731-02-3Relevant academic research and scientific papers
Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1- a]isoquinoline derivatives
Goldbrunner, Michael,Loidl, Günther,Polossek, Thomas,Mannschreck, Albrecht,Von Angerer, Erwin
, p. 3524 - 3533 (1997)
6-Alkyl-12-formyl-5,6-dihydroindolo[2,1-α]isoquinolines have been shown to inhibit the growth of human mammary carcinoma cells by an unknown mode of action. One of the possible molecular targets is the tubulin system which is involved in Cell division. A
