195816-25-2

Basic information

• Product Name: 2-Oxazolidinone, 3-[3-fluoro-4-[1,2,3,6-tetrahydro-1-(phenylmethyl)-4-pyridinyl]phenyl]-5-( hydroxymethyl)-, (5R)-
• CAS NO: 195816-25-2
• Molecular Formula: C22H23FN2O3
• Molecular Weight: 382.435
• Mol File: 195816-25-2.mol

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-[3-fluoro-4-[1,2,3,6-tetrahydro-1-(phenylmethyl)-4-pyridinyl]phenyl]-5-( hydroxymethyl)-, (5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-[3-fluoro-4-[1,2,3,6-tetrahydro-1-(phenylmethyl)-4-pyridinyl]phenyl]-5-( hydroxymethyl)-, (5R)-(195816-25-2)
• EPA Substance Registry System: 2-Oxazolidinone, 3-[3-fluoro-4-[1,2,3,6-tetrahydro-1-(phenylmethyl)-4-pyridinyl]phenyl]-5-( hydroxymethyl)-, (5R)-(195816-25-2)

Safety Data

• Hazardous Substances Data: 195816-25-2(Hazardous Substances Data)

Upstream product

• 195817-61-9 4-(1-benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-3-fluoro-phenylamine 

Downstream Products

• 195816-24-1 (S)-N-{3-[3-fluoro-4-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)phenyl]-2-oxooxazolidin-5-yl-methyl}acetamide 
• 188974-29-0 (S)-(-)-N-[[2-oxo-3-[4-(4-piperidinyl)-3-fluorophenyl]-5-oxazolidinyl]methyl]acetamide 
• 188974-48-3 (S)-(-)-N-[[2-oxo-3-[4-(3,6-dihydro-2H-pyridin-4-yl)-3-fluorophenyl]-5-oxazolidinyl]methyl]acetamide 
• 371195-46-9 (R)-N-{3-[3-fluoro-4-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)phenyl]-2-oxooxazolidin-5-yl-methyl}azide 
• 252328-94-2 5(R)-Isoxazol-3-yloxymethyl-3-(4-(1-benzyl-1,2,5,6-tetrahydropyrid-4-yl)-3-fluorophenyl)oxazolidin-2-one 
• 264600-46-6 5(R)-[N-isoxazol-3-yl-N-(2,2,2-trichloroethyloxycarbonyl)aminomethyl]-3-[3-fluoro-4-(1-benzyl-1,2,5,6-tetrahydropyrid-4-yl)phenyl]oxazolidin-2-one 
• 371194-87-5 (5R)-3-(4-(1-benzyl-1,2,5,6-tetrahydropyridin-4-yl)-3-fluorophenyl)-5-(tetrazol-1-ylmethyl)oxazolidin-2-one 
• 252342-23-7 acetic acid 2-(4-{2-fluoro-4-[2-oxo-5-([1,2,5]thiadiazol-3-yloxymethyl)-oxazolidin-3-yl]-phenyl}-3,6-dihydro-2H-pyridin-1-yl)-2-oxo-ethyl ester 
• 783291-36-1 (R)-3-[3-Fluoro-4-(1,2,3,6-tetrahydro-pyridin-4-yl)-phenyl]-5-([1,2,5]thiadiazol-3-yloxymethyl)-oxazolidin-2-one 

Relevant articles and documents

Antibiotic oxazolidinone derivatives

The invention concerns a compound of the formula (I): wherein, for example: R1is of the formula —NHC(═O)Rbwherein Rbis, for example, (1-4C)alkyl; R2and R3are hydrogen or fluoro; R2and R3are hydrogen or fluoro; D is O; R4and R5are hydrogen, (1-4C)alkyl or AR-oxymethyl; AR is phenyl or phenyl(1-4C)alkyl; R6is hydrogen; >A—B— is of the formula >C═C(Ra)—, >CHCHRa—, or >C(OH)CHRa— (> represents two single bonds) wherein Rais hydrogen or (1-4C)alkyl; and pharmaceutically-acceptable salts thereof; processes for their preparation; pharmaceutical compositions containing them and their use as antibacterial agents.

Antibiotic oxazolidinone derivatives

The invention concerns a compound of formula (I): STR1 wherein R1 -R6, A, B, and D have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising