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4-(2-benzyloxycarbonylamino-2-carboxy-ethyl)-piperidine-1-carboxylic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

195877-38-4

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195877-38-4 Usage

Chemical structure

complex structure with a piperidine ring, a carboxylic acid group, and a tert-butyl ester moiety

Functional groups present

benzyloxycarbonylamino group, carboxy-ethyl group

Usage

research and chemical synthesis as a building block for pharmaceuticals and other organic compounds

Importance of tert-butyl ester group

provides stability and protection for the carboxylic acid functionality, making it a useful intermediate in organic chemistry

Potential applications

medicinal chemistry and drug development due to structural features

Check Digit Verification of cas no

The CAS Registry Mumber 195877-38-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,8,7 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 195877-38:
(8*1)+(7*9)+(6*5)+(5*8)+(4*7)+(3*7)+(2*3)+(1*8)=204
204 % 10 = 4
So 195877-38-4 is a valid CAS Registry Number.

195877-38-4Relevant academic research and scientific papers

Solution-phase and solid-phase synthesis of novel transition state inhibitors of coagulation enzymes incorporating a piperidinyl moiety

Adang, Anton E. P.,Peters, Co A. M.,Gerritsma, Siene,De Zwart, Edwin,Veeneman, Gerrit

, p. 1227 - 1232 (1999)

2-Amino-3-piperidin-4-yl-propionic acid containing peptidomimetics are potent protease inhibitors when combined with an appropriate keto-thiazole or keto-carboxylic acid moiety. A novel P1 residue in factor Xa and thrombin inhibitors has been found resulting in IC50 values as low as 0.048 μM, a factor of ten more potent than Argatroban. Starting with non-chiral synthetic routes, a new stereospecific route was developed as well as a new solid- phase method.

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