19598-06-2

Basic information

• Product Name: 1,2-dimethoxy-2,3-dihydro-1H-indene
• CAS NO: 19598-06-2
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.2277
• Mol File: 19598-06-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 249.3°C at 760 mmHg
• Flash Point: 92.9°C
• Density: 1.06g/cm³
• Vapor Pressure: 0.0365mmHg at 25°C
• Refractive Index: 1.526
• CAS DataBase Reference: 1,2-dimethoxy-2,3-dihydro-1H-indene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dimethoxy-2,3-dihydro-1H-indene(19598-06-2)
• EPA Substance Registry System: 1,2-dimethoxy-2,3-dihydro-1H-indene(19598-06-2)

Safety Data

• Hazardous Substances Data: 19598-06-2(Hazardous Substances Data)

Usage

General Description

1,2-dimethoxy-2,3-dihydro-1H-indene is a chemical compound with the molecular formula C11H14O2. It is a white to slightly yellow crystalline solid with a faint odor. 1,2-dimethoxy-2,3-dihydro-1H-indene is used in the production of various pharmaceuticals and agrochemicals due to its ability to act as a precursor in organic synthesis. It is also used as an intermediate in the manufacturing of perfumes and fragrances. Additionally, it can be used as a building block in the synthesis of other organic compounds. Its unique structure and properties make it a versatile and valuable chemical in the pharmaceutical and chemical industries.

Upstream product

• 67-56-1 methanol 
• 95-13-6 1-indene 

Relevant articles and documents

Electrochemical cleavage of double bonds in conjugated cycloalkenyl- and 1,2-alkenobenzenes

The electrochemical cleavage of olefinic bonds in conjugated C5-C7-cycloalkenylbenzenes 1, indene 4a, and 1,2-dihydronaphthalene (4b) results from anodic oxidation of these compounds in MeOH in an undivided cell. The process includes the formation of (1,2-dimethoxycycloalkyl)benzenes 2a-c, 1,2-dimethoxyindan (5a), and 1,2-dimethoxytetralin (5b) as intermediates and leads to ω,ω-dimethoxy-ω-phenyl-n-C5-C7-alkanal dimethyl acetals 3a-c, [2-(dimethoxymethyl)phenyl]ethanal dimethyl acetal (6a), and 3-[2-(dimethoxymethyl)phenyl]propanal dimethyl acetal (6b) as major products, respectively. The best yields of 3a-c and 6a,b (58-76%) were obtained when the electrolysis was carried out at 60°C and 6 F/mol of electricity based on 1, 4a, and 4b was passed using C-anode and Bu4NBF4 as a supporting electrolyte. Compounds 2a-c and 5a,b as mixtures of cis and trans diastereomers were obtained as major products in 81-90% yield when the electrolysis was terminated after 2 F/mol of electricity based on 1, 4a, and 4b had been passed. The cis/trans ratio in 2a-c was increased with the increasing the size of cycloalkane rings in 1, 4a, and 4b and the obvious stereoselective effect of the anode nature (C or Pt) being observed in the case of dimethoxylation of 4a.