19611-45-1

Basic information

• Product Name: 2H-PYRAN-2-CARBOXALDEHYDE, TETRAHYDRO-
• Synonyms: 2H-PYRAN-2-CARBOXALDEHYDE, TETRAHYDRO-;TETRAHYDRO-2H-PYRAN-2-CARBALDEHYDE;TETRAHYDRO-PYRAN-2-CARBALDEHYDE;tetrahydro-2H-pyran-2-carbaldehyde(SALTDATA: FREE)
• CAS NO: 19611-45-1
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.14
• Mol File: 19611-45-1.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 2H-PYRAN-2-CARBOXALDEHYDE, TETRAHYDRO-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-PYRAN-2-CARBOXALDEHYDE, TETRAHYDRO-(19611-45-1)
• EPA Substance Registry System: 2H-PYRAN-2-CARBOXALDEHYDE, TETRAHYDRO-(19611-45-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 19611-45-1(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 50-00-0 formaldehyd 
• 201230-82-2 carbon monoxide 
• 100-72-1 Tetrahydropyran-2-methanol 
• 79-37-8 oxalyl dichloride 
• 110811-44-4 2,6-Dibromo-hexanal 
• 100-73-2 acrolein dimer 

Downstream Products

• 100-72-1 Tetrahydropyran-2-methanol 
• 1030623-66-5 2-amino-6-mercapto-4-(tetrahydro-2H-pyran-2-yl)pyridine-3,5-dicarbonitrile 
• 502-44-3 hexahydro-2H-oxepin-2-one 
• 77342-77-9 1,2-Diphenyl-5-(tetrahydropyran-2-yl)pyrrol 
• 77342-67-7 4-Phenyl-1-(tetrahydropyran-2-yl)-1,4-butandion 
• 1155904-79-2 N-benzyl-1-(tetrahydro-2H-pyran-2-yl)methanamine 

Relevant articles and documents

Synthesis of an Azaphosphatriptycene and Its Rhodium Carbonyl Complex

A 10-aza-9-phosphatriptycene is accessible on a gram scale, in three laboratory steps from commercially available precursors. Infrared spectroscopy of a rhodium(I) carbonyl complex bearing this ligand reflects the weak σ-donor/strong π-acceptor character of the phosphine; the solid-state structure reveals moderate steric demand. This ligand supports highly active catalysts for the hydroformylation of cyclic alkenes.

HETEROCYCLIC AMIDES AS KINASE INHIBITORS

Disclosed are compounds having the formula: (I) wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.

Hydroformylation and hydroalkylcarbonylation of 3,4-dihydro[2H]pyran catalysed by Co2(CO)8 under syngas conditions

In the cobalt-catalysed hydroformylation of 3,4-dihydro[2H]pyran, the influence of different reaction parameters such as time, pressure, triphenylphosphine addition, catalyst and substrate concentration has been investigated. 2-formyl-tetrahydropyran, tetrahydropyran and a hydroalkylcarbonylation product were the main reaction products. The selectivity towards 2-formyl-tetrahydropyran formation is favoured at constant catalyst and substrate concentration. The coordination of the pyran's oxygen to the cobalt atom seems to be an important intermediate for the formation of 2-formyl-tetrahydropyran. Different substrate or catalyst concentrations promote the formation of other reduced products. The addition of triphenylphosphine to the catalyst leads to a less active species, which decreases the yield and promotes the hydroalkylcarbonylation reaction.