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1H-2-Benzopyran, 1-(4-chlorophenyl)-3,4-dihydro- is a chemical compound belonging to the class of benzopyrans, which are derivatives of the benzopyran heterocyclic ring system. This specific compound features a 4-chlorophenyl group attached to the 1-position of the benzopyran core, and it is a dihydro derivative, meaning that it has two hydrogen atoms added to the molecule, resulting in a partially saturated structure. It is an organic compound with potential applications in the synthesis of pharmaceuticals and other organic compounds due to its unique structure and functional groups.

1962-27-2

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1962-27-2 Usage

Chemical class

Benzopyran derivatives

Substitution

1-(4-chlorophenyl) at the 1 position, 3,4-dihydroat the 3,4 positions of the benzopyran ring

Potential biological activities

Anti-inflammatory, neuroprotective, and antioxidant effects

Industrial use

Synthesis of various drugs

Research use

Medicinal chemistry research tool

Check Digit Verification of cas no

The CAS Registry Mumber 1962-27-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,6 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1962-27:
(6*1)+(5*9)+(4*6)+(3*2)+(2*2)+(1*7)=92
92 % 10 = 2
So 1962-27-2 is a valid CAS Registry Number.

1962-27-2Relevant academic research and scientific papers

Zeolite-catalyzed simple synthesis of isochromans via the oxa-Pictet-Spengler reaction

Hegedues, Adrienn,Hell, Zoltan

, p. 1220 - 1222 (2006)

The synthesis of isochromans via oxa-Pictet-Spengler reaction using a modified small pore size zeolite E4 as catalyst was investigated. Ersorb-4 (E4) is a clinoptylolite-type zeolite material with high silicon content. The reaction of 2-phenylethanol deri

Efficient C(sp3)-H bond functionalization of isochroman by azadol catalysis

Muramatsu, Wataru,Nakano, Kimihiro

supporting information, p. 1549 - 1552 (2015/03/30)

A novel organocatalytic C(sp3)-H bond functionalization of isochroman under practical conditions has been developed. In the presence of 5.0 mol % of AZADOL, the catalysis proceeded successfully with a broad range of substrates and nucleophiles in excellent yields.

Organocatalytic approach for C(sp3)-H bond arylation, alkylation, and amidation of isochromans under facile conditions

Muramatsu, Wataru,Nakano, Kimihiro

supporting information, p. 2042 - 2045 (2014/05/06)

A new catalytic approach for the synthesis of isochroman derivatives via direct C(sp3)-H bond arylation is described. The oxidation reaction with [bis(trifluoroacetoxy)iodo]benzene facilitates the regeneration of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone in the C(sp3)-H bond arylation of isochroman. The reaction conditions can also be used for alkyl Grignard reagents and amides to afford the corresponding isochroman derivatives.

Simple and direct sp3 C-H bond arylation of tetrahydroisoquinolines and isochromans via 2,3-dichloro-5,6-dicyano-1,4- benzoquinone oxidation under mild conditions

Muramatsu, Wataru,Nakano, Kimihiro,Li, Chao-Jun

supporting information, p. 3650 - 3653 (2013/08/23)

The 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-mediated sp3 C-H bond arylation of tetrahydroisoquinolines and isochromans is described. The corresponding products were facilely synthesized via a simple nucleophilic addition reaction betwee

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