196494-84-5

Upstream product

• 100-46-9 benzylamine 
• 100227-29-0 5,6-di-O-isopropylidene-D-glucono-1,4-lactone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 196494-81-2 2,3-bis-O-(tert-butyldimethylsilyl)-5,6-O-isopropylidene-D-glucono-1,4-lactone 
• 280561-89-9 (1R,2S,3S)-2,3-Bis-(tert-butyl-dimethyl-silanyloxy)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butane-1,4-diol 

Relevant academic research and scientific papers

Inhibition of UDP-Gal mutase and mycobacterial galactan biosynthesis by pyrrolidine analogues of galactofuranose

Some pyrrolidine analogues of galactofuranose - synthesised from carbohydrate lactones - are the first known inhibitors of E. coli K12 UDP-Gal mutase and mycobacterial galactan biosynthesis. This inhibition may form chemotherapeutic strategy for the treatment of human pathogens which contain integral galactofuranosyl structures such as tuberculosis and leprosy.