1965-55-5

Basic information

• Product Name: 4-nitro-N-2-chloroethylaniline
• Synonyms: 4-nitro-N-2-chloroethylaniline
• CAS NO: 1965-55-5
• Molecular Weight: 200.625
• Mol File: 1965-55-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-nitro-N-2-chloroethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitro-N-2-chloroethylaniline(1965-55-5)
• EPA Substance Registry System: 4-nitro-N-2-chloroethylaniline(1965-55-5)

Safety Data

• Hazardous Substances Data: 1965-55-5(Hazardous Substances Data)

Upstream product

• 870-24-6 2-chloroethanamine hydrochloride 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 446292-04-2 4-(4-nitrophenyl)-3-morpholinone 
• 438056-69-0 4-(4-aminophenyl)morpholin-3-one 

Relevant articles and documents

Preparation method of 4-(4-aminophenyl)-3-molindone

The invention provides a preparation method of 4-(4-aminophenyl)-3-molindone. The preparation method has the advantages that reaction steps with high risk and high environmental pressure are omitted,especially the use of mixed acid and chloroacetyl chloride is avoid, so that the pressure of environmental protection is reduced; in addition, the use of strong oxidants such as potassium permanganateis avoided, so that the production of by-products is reduced, the synthesis yield is high, the product quality is good and the purification of reaction post treatment is facilitated; besides, all thesteps related in the reaction process are easy to carry out, so that the reaction in which passivation effect of functional groups and the like are difficult to generate in an existing method is avoided, for example, the route which takes p-nitroaniline as a raw material to carry out substitution reaction is almost impossible to perform; besides, the selected raw materials such as p-fluoronitrobenzene and bromoethylamine hydrobromide, disclosed by the invention are easy to obtain; compared with the molindone and other raw materials involved in the existing method, the preparation method is low in price and is suitable for industrialized production.