19679-84-6 Usage
General Description
Phenyl tetrahydrofuran-2-carboxylate is a chemical compound with the molecular formula C12H14O3. It is a carboxylate ester, and its structure includes a phenyl group attached to a tetrahydrofuran ring with a carboxylic acid functional group. phenyl tetrahydrofuran-2-carboxylate is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceutical products. It has also been studied for its potential use in organic chemistry and medicinal chemistry research. Phenyl tetrahydrofuran-2-carboxylate may have applications in the development of new drug candidates and therapeutic agents due to its structural properties and potential pharmacological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 19679-84-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,7 and 9 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19679-84:
(7*1)+(6*9)+(5*6)+(4*7)+(3*9)+(2*8)+(1*4)=166
166 % 10 = 6
So 19679-84-6 is a valid CAS Registry Number.
19679-84-6Relevant articles and documents
Substituted tetrahydrofuroyl-1-phenylalanine derivatives as potent and specific VLA-4 antagonists
Doherty, George A.,Yang, Ginger X.,Borges, Edite,Chang, Linda L.,MacCoss, Malcolm,Tong, Sharon,Kidambi, Usha,Egger, Linda A.,McCauley, Ermenegilda,Van Riper, Gail,Mumford, Richard A.,Schmidt, John A.,Hagmann, William K.
, p. 1501 - 1505 (2007/10/03)
A series of substituted tetrahydrofuroyl-1-phenylalanine derivatives was prepared and evaluated as VLA-4 antagonists. Substitution of the α carbon of the tetrahydrofuran with aryl groups increased the specificity for VLA-4 versus α4β7 while amide substitution increased the potency of the series without increasing the specificity. Substitution of the β carbon of the tetrahydrofuran with keto or amino groups slightly improved the specificity for VLA-4 versus α4β7 but with a significant loss in binding affinity for VLA-4.
