19679-84-6 Usage
Uses
Used in Pharmaceutical Industry:
Phenyl tetrahydrofuran-2-carboxylate is utilized as a key intermediate in the synthesis of a variety of drugs and pharmaceutical products. Its unique structural properties make it a valuable component in the development of new medications.
Used in Organic Chemistry Research:
phenyl tetrahydrofuran-2-carboxylate serves as a subject of study in organic chemistry, where its reactivity and potential for forming new compounds are explored. Its carboxylate ester nature allows for various reactions that can lead to the creation of novel organic molecules.
Used in Medicinal Chemistry Research:
Phenyl tetrahydrofuran-2-carboxylate is also considered in medicinal chemistry for its potential to contribute to the development of new drug candidates and therapeutic agents. Its structural features and possible pharmacological activities are of interest to researchers seeking to advance the field of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 19679-84-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,7 and 9 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19679-84:
(7*1)+(6*9)+(5*6)+(4*7)+(3*9)+(2*8)+(1*4)=166
166 % 10 = 6
So 19679-84-6 is a valid CAS Registry Number.
19679-84-6Relevant academic research and scientific papers
Substituted tetrahydrofuroyl-1-phenylalanine derivatives as potent and specific VLA-4 antagonists
Doherty, George A.,Yang, Ginger X.,Borges, Edite,Chang, Linda L.,MacCoss, Malcolm,Tong, Sharon,Kidambi, Usha,Egger, Linda A.,McCauley, Ermenegilda,Van Riper, Gail,Mumford, Richard A.,Schmidt, John A.,Hagmann, William K.
, p. 1501 - 1505 (2007/10/03)
A series of substituted tetrahydrofuroyl-1-phenylalanine derivatives was prepared and evaluated as VLA-4 antagonists. Substitution of the α carbon of the tetrahydrofuran with aryl groups increased the specificity for VLA-4 versus α4β7 while amide substitution increased the potency of the series without increasing the specificity. Substitution of the β carbon of the tetrahydrofuran with keto or amino groups slightly improved the specificity for VLA-4 versus α4β7 but with a significant loss in binding affinity for VLA-4.
