196807-44-0Relevant academic research and scientific papers
β-selective C-glycosidations: Lewis-acid mediated reactions of carbohydrates with silyl ketene acetals
Minehan, Thomas G.,Kishi, Yoshito
, p. 6815 - 6818 (1997)
Several examples of β-selective C-glycosidation reactions, involving TMSOTf-promoted addition of sterically hindered silyl ketene acetals to glucosyl and galactosyl acetates, are presented.
A practical route to 3,6-dideoxyhexoses
Yu, Henry N.,Zhang, Ping,Ling, Chang-Chun,Bundle, David R.
, p. 465 - 479 (2000)
Novel, readily scaled and practical routes for the synthesis of 3,6-dideoxy-D-xylo-hexose and 3,6-dideoxy-D-ribo-hexose and their corresponding glycosyl donors are presented. The method uses a 1,2-O-propylidene acetal to protect the monosaccharides, glucose and galactose, thereby permitting not only easy modification at both 3 and 6 positions, but also the opportunity to readily place different protecting groups on OH-2 and OH-4. Copyright (C) 2000 Elsevier Science Ltd.
