19687-73-1

Usage

Uses

Used in Environmental Contaminant Detection:
2-NP-AOZ is used as a marker for detecting environmental contaminants, particularly those related to Furazolidone and Nitrofuran. Its presence in environmental samples can indicate contamination from these substances, which are of concern due to their potential harmful effects.
Used in Food Contaminant Analysis:
In the food industry, 2-NP-AOZ is utilized as an analytical tool for identifying food contaminants. Its detection in food products can signal the presence of harmful substances, allowing for appropriate measures to be taken to ensure food safety.
Used in Heat Processing Contaminant Identification:
2-NP-AOZ is employed as an indicator for heat processing contaminants in various industries. Its identification in heat-processed products can help determine the presence of unwanted substances, which may be a result of improper processing techniques or contamination during production.

InChI:InChI=1/C10H9N3O4/c14-10-12(5-6-17-10)11-7-8-3-1-2-4-9(8)13(15)16/h1-4,7H,5-6H2/b11-7+

Upstream product

• 80-65-9 3-amino-2-oxazolidinone 
• 552-89-6 2-nitro-benzaldehyde 
• 19693-49-3 N'-(2-Nitro-benzyliden)-hydrazincarbonsaeure-(2-hydroxy-aethylester) 
• 19693-50-6 (2-nitro-benzylidene)-hydrazinecarboxylic acid 2-chloro-ethyl ester 

Downstream Products

• 19687-74-2 3-(2-amino-benzylideneamino)-oxazolidin-2-one 
• 19687-90-2 3-[2-(2,2-dichloro-acetylamino)-benzylideneamino]-oxazolidin-2-one 

Relevant academic research and scientific papers

Determination of nitrofuran residues in tilapia tissue by enzyme-linked immunosorbent assay and confirmation by liquid chromatography tandem mass spectrometric detection

Furazolidone is a broad-spectrumantibiotic that is frequently used in aquaculture on account of its excellent antibacterial properties. In this study, both the enzyme-linked immunosorbent assay (ELISA) and high-performance liquid chromatography-tandemmass

Plant Uptake and Metabolism of Nitrofuran Antibiotics in Spring Onion Grown in Nitrofuran-Contaminated Soil

Environmental pollution caused by the discharge of mutagenic and carcinogenic nitrofurans to the aquatic and soil environment is an emerging public health concern because of the potential in producing drug-resistant microbes and being uptaken by food crops. Using liquid chromatography-tandem mass spectrometry analysis and with spring onion (Allium wakegi Araki) as the plant model, we investigated in this study the plant uptake and accumulation of nitrofuran from a contaminated environment. Our study revealed for the first time high uptake and accumulation rates of nitrofuran in the edible parts of the food crop. Furthermore, results indicated highly efficient plant metabolism of the absorbed nitrofuran within the plant, leading to the formation of genotoxic hydrazine-containing metabolites. The results from this study may disclose a previously unidentified human exposure pathway through contaminated food crops.

Biotransformation of furaltadone by pig hepatocytes and Salmonella typhimurium TA 100 bacteria, and the formation of protein-bound metabolites

The major metabolite resulting from the biotransformation of furaltadone (5-morpholinomethyl-3-[5-nitrofurfurylidene-amino]-2-oxazolidinone) by pig hepatocytes was shown to result from the N-oxidation of the tertiary nitrogen in the morpholino-ring, lcavi