19693-54-0 Usage
Class
Naphthyridines
Naphthyridines are heterocyclic compounds containing a naphthyridine moiety, which is a fused tricyclic 5-amino form of pyridine.
Derivative
Naphthyridin-5(6H)-one
The compound is a derivative of naphthyridin-5(6H)-one, with a methyl group attached to the sixth carbon atom.
Structural Feature
Methyl group at the sixth carbon atom
The compound has a methyl group (CH3) attached to the sixth carbon atom, which distinguishes it from other naphthyridin-5(6H)-one derivatives.
Application
Pharmaceutical and research
The compound is used as a building block for the synthesis of various biologically active compounds in the field of pharmaceuticals and research.
Potential Applications
Drug discovery and development
It has potential applications in drug discovery and development, particularly in the design and synthesis of new therapeutic agents.
CAS Registry Numbers
8CI, 9CI
The compound is identified by two different CAS Registry Numbers, which are unique identifiers for chemical substances.
Heterocyclic Compound
Yes
The compound is a heterocyclic compound, which means it contains a ring of atoms with at least one heteroatom (in this case, nitrogen).
Biological Activity
Unknown
The specific biological activity of this compound is not provided in the material, but it is used as a building block for the synthesis of biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 19693-54-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,9 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19693-54:
(7*1)+(6*9)+(5*6)+(4*9)+(3*3)+(2*5)+(1*4)=150
150 % 10 = 0
So 19693-54-0 is a valid CAS Registry Number.
19693-54-0Relevant articles and documents
SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF
-
, (2019/10/15)
The present disclosure relates to novel compounds including formula (X) and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with SHP2 deregulation with the compounds and compositions of the disclosure.
A Convenient Synthesis of 5-Keto-6-methyl-5,6-dihydro-1,6-naphthyridine
Jhalani, Vinod K.,Usgaonkar, Ramesh N.
, p. 916 (2007/10/02)
The reaction of DMF-POCl3 with ethyl 3-carboxy-2-pyridylacetate (I) leads to the formation of 8-carboxy-5-keto-6-methyl-5,6-dihydro-1,6-naphthyridine (III) through the intermediate 8-(N,N-dimethylaminomethylene)pyranopyridine-5,7-dione (II).Compound III, on pyrolysis, undergoes decarboxylation to give 5-keto-6-methyl-5,6-dihydro-1,6-naphthyridine (IV).
