196958-41-5

Upstream product

• 932-52-5 5-Aminouracil 
• 90-60-8 3,5-dichlorosalicyclaldehyde 

Downstream Products

• 269393-00-2 C₁₃H₁₄Cl₂N₃O₆P 
• 269393-07-9 C₁₇H₁₄Cl₂F₈N₃O₆P 
• 269393-04-6 C₁₇H₂₂Cl₂N₃O₆P 
• 269393-05-7 dibutyl [(3,5-dichloro-2-hydroxyphenyl)[(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)amino]methyl]phosphonate 
• 1225188-60-2 C₁₉H₂₆Cl₂N₃O₆P 

Relevant academic research and scientific papers

5-Arylideneaminouracyls: IV. Phosphorylated derivatives and their biological activity

It extension of the studies on the search for the new biologically active 5-aminouracyl derivatives, we synthesized by the reaction of dialkylphosphites with arylideneuracils respective aminomethylphosphonates. The high level of the antiviral and anti-mycobacterial activity of the target compounds correlates well with the physicochemical parameters characterizing their structure.

5-Arylideneaminouracils: I. Synthesis and relations between physicochemical parameters and biological activity

A number of 5-arylideneaminouracils were synthesized by condensation of 5-aminouracil with substituted aromatic aldehydes. Correlation analysis according to Hantzsch revealed strong effects of the lipophilicity parameter and hydration energy of these comp