19699-10-6

Usage

Uses

Used in Fragrance Industry:
2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide is utilized as a fragrance ingredient for its ability to impart pleasant and distinctive scents to various products. Its use in this industry is driven by the need for creating appealing and long-lasting aromas in perfumes, colognes, and other scented products.
Used in Cosmetic and Personal Care Products:
In the cosmetic and personal care industry, 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide serves as a masking agent. It is employed to conceal or reduce the intensity of undesirable odors in products such as shampoos, soaps, and lotions, thereby enhancing the overall sensory experience for the consumer.
Used in Food Industry:
As a flavoring agent, 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide is incorporated into food products to enhance or modify their taste profiles. Its use in this industry is motivated by the desire to create unique and appealing flavors that can attract consumers and differentiate products in the market.
Used in Regulatory Compliance:
Given its identification as a potential allergen, 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide is subject to regulations and restrictions in some countries. This aspect of its use underscores the importance of adhering to safety standards and ensuring that the compound is used responsibly and within the limits set by regulatory bodies.

Upstream product

• 3282-30-2 pivaloyl chloride 
• 88-05-1 2,4,6-trimethylaniline 
• 75-98-9 Trimethylacetic acid 
• 57116-96-8 2-mesityl isocyanide 
• 89379-02-2 tert-butylmercury iodide 
• 38442-51-2 tert-butylmercury chloride 
• 73838-84-3 Bis(3,3-dimethyl-1-butynyl)mercury 

Relevant academic research and scientific papers

Organocatalytic Enantioselective Synthesis of Atropisomeric Aryl-p-Quinones: Platform Molecules for Diversity-Oriented Synthesis of Biaryldiols

Presented here is a class of novel axially chiral aryl-p-quinones as platform molecules for the preparation of non-C2 symmetric biaryldiols. Two sets of aryl-p-quinone frameworks were synthesized with remarkable enantiocontrol by means of chiral phosphoric acid catalyzed enantioselective arylation of p-quinones by central-to-axial chirality conversion. These aryl-p-quinones were then used to access a wide spectrum of highly functionalized non-C2 symmetric biaryldiols with excellent retention of the enantiopurity.

Amine Activation: Synthesis of N-(Hetero)arylamides from Isothioureas and Carboxylic Acids

A novel method for N-(hetero)arylamide synthesis based on rarely explored amine activation, rather than classical acid activation, is reported. The activated amines are easily prepared using a three-component reaction with commercial reagents. The new method shows a broad scope including challenging amides not (efficiently) accessible via classical protocols.

Facile synthesis of phosphaamidines and phosphaamidinates using nitrilium ions as an imine synthon

Readily accessible nitrilium triflates are convenient imine building blocks for the expedient synthesis of a novel class of 1,3-P,N ligands as demonstrated for the reaction with primary phosphanes. This procedure allows variation of all substituents. X-ray crystal structures are reported for nitrilium ions, phosphaamidines, and three phosphaamidinate complexes. The lithium phosphaamidinate is N coordinated and its reaction with [AuCl(tht)] (tht=tetrahydrothiophene) gives a unique P-bridged gold trimer, while a P,N-bidentate complex results from [{RhCl(cod)}2]. The nitrilium ion methodology allows extension of the 1,3-P,N motive to bis(imino)phosphanes, which are the neutral phosphorus analogues of the valuable β-diketiminate ligand.

Electron transfer chain reactions in the alkylation of isonitriles by alkylmercury halides

Imidoyl (PhN=CR) or acyl (RCO) radicals undergo electron transfer to alkylmercury halides in Me2SO or PhH solution. Addition of t-Bu or i-Pr to isonitriles followed by electron transfer forms the nitrilium ion which is converted into the amide in Me2SO, into the imidoyl halide in PhH, and into the amidine in PhH solution containing primary or secondary amines. Acta Chemica Scandinavica 1998.