19699-10-6

Basic information

• Product Name: 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide
• Synonyms: N1-mesityl-2,2-dimethylpropanamide; N-Mesityl-2,2-dimethylpropanamide; propanamide, 2,2-dimethyl-N-(2,4,6-trimethylphenyl)-
• CAS NO: 19699-10-6
• Molecular Formula: C₁₄H₂₁NO
• Molecular Weight: 219.3226
• Mol File: 19699-10-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 327.1°C at 760 mmHg
• Flash Point: 197.4°C
• Density: 0.992g/cm³
• Vapor Pressure: 0.000207mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide(19699-10-6)
• EPA Substance Registry System: 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide(19699-10-6)

Safety Data

• Hazardous Substances Data: 19699-10-6(Hazardous Substances Data)

Usage

General Description

2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide is a chemical compound that belongs to the amide class. It is a white to off-white crystalline powder with a molecular formula of C16H25NO and a molecular weight of 247.4 g/mol. 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide is commonly used as a fragrance ingredient and as a masking agent in various cosmetic and personal care products. It is also used as a flavoring agent in food products. Additionally, it has been identified as a potential allergen and is subject to regulations and restrictions in some countries. Overall, 2,2-dimethyl-N-(2,4,6-trimethylphenyl)propanamide is a versatile compound with various applications in the fragrance, cosmetic, and food industries.

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Relevant articles and documents

Organocatalytic Enantioselective Synthesis of Atropisomeric Aryl-p-Quinones: Platform Molecules for Diversity-Oriented Synthesis of Biaryldiols

Presented here is a class of novel axially chiral aryl-p-quinones as platform molecules for the preparation of non-C2 symmetric biaryldiols. Two sets of aryl-p-quinone frameworks were synthesized with remarkable enantiocontrol by means of chiral phosphoric acid catalyzed enantioselective arylation of p-quinones by central-to-axial chirality conversion. These aryl-p-quinones were then used to access a wide spectrum of highly functionalized non-C2 symmetric biaryldiols with excellent retention of the enantiopurity.

Facile synthesis of phosphaamidines and phosphaamidinates using nitrilium ions as an imine synthon

Readily accessible nitrilium triflates are convenient imine building blocks for the expedient synthesis of a novel class of 1,3-P,N ligands as demonstrated for the reaction with primary phosphanes. This procedure allows variation of all substituents. X-ray crystal structures are reported for nitrilium ions, phosphaamidines, and three phosphaamidinate complexes. The lithium phosphaamidinate is N coordinated and its reaction with [AuCl(tht)] (tht=tetrahydrothiophene) gives a unique P-bridged gold trimer, while a P,N-bidentate complex results from [{RhCl(cod)}2]. The nitrilium ion methodology allows extension of the 1,3-P,N motive to bis(imino)phosphanes, which are the neutral phosphorus analogues of the valuable β-diketiminate ligand.