197218-96-5Relevant academic research and scientific papers
Ethyl 3-iodo-4,4,4-trifluoro-2(Z)-butenoate: Regio- and stereo-specific preparation and palladium-catalyzed reaction with terminal alkynes
Qing, Feng-Ling,Zhang, Yanmei
, p. 6729 - 6732 (1997)
Ethyl 3-iodo-4,4,4-trifluoro-2(Z)-butenoate (2) was regio- and stereospecific prepared from ethyl 4,4,4-trinuoro-2-butynote (1). The Sonogashira reaction of 2 with terminal alkynes afforded the (2Z)-en-4-ynoic acid derivatives containing trifluoromethyl g
A stereoselective synthesis of ethyl 9-cis-7,8-didehydro-19-trifluoromethylretinoate
Qing, Feng-Ling,Ying, Jieweng,Zhang, Yanmei
, p. 31 - 33 (2007/10/03)
The design and synthesis of ethyl 9-cis-7,8-didehydro-19-trifluoromethylretinoate was described. The key step is the Sonogashira reaction of ethyl 3-iodo-4,4,4-trifluoro-2(Z)-butenoate 2 with terminal alkyne 3.
