
Tetrahedron Letters p. 6729 - 6732 (1997)
Update date:2022-08-04
Topics:
Qing, Feng-Ling
Zhang, Yanmei
Ethyl 3-iodo-4,4,4-trifluoro-2(Z)-butenoate (2) was regio- and stereospecific prepared from ethyl 4,4,4-trinuoro-2-butynote (1). The Sonogashira reaction of 2 with terminal alkynes afforded the (2Z)-en-4-ynoic acid derivatives containing trifluoromethyl g
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(1968)