197231-58-6Relevant academic research and scientific papers
Enantioselective synthesis of (S)-Vigabatrin
Alcon, Montserrat,Poch, Marta,Moyano, Albert,Pericas, Miquel A.,Riera, Antoni
, p. 2967 - 2974 (2007/10/03)
An asymmetric synthesis of fully protected (S)-Vigabatrin has been developed. The key intermediate in the sequence is enantiomerically pure N-Boc-5-phenyl-3-amino-1,2-diol 5a, obtained from (E)-5-phenyl-2-penten-1-ol by employing a catalytic Sharpless epo
