197239-49-9

Usage

Uses

Used in Organic Synthesis:
2-Fluoro-4-(trifluoromethyl)benzyl alcohol is utilized as an intermediate in organic synthesis, leveraging its distinctive fluorinated and trifluoromethylated structure to facilitate the creation of a wide range of complex organic molecules. Its presence in these syntheses is crucial for imparting specific properties to the final products, such as enhanced reactivity, stability, or selectivity in chemical reactions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-Fluoro-4-(trifluoromethyl)benzyl alcohol serves as a valuable component in drug discovery and development. Its unique chemical properties allow it to be incorporated into the design of new pharmaceutical agents, potentially leading to the development of novel drugs with improved efficacy, selectivity, and pharmacokinetic profiles.
Used as a Reagent:
2-Fluoro-4-(trifluoromethyl)benzyl alcohol is also employed as a reagent in the preparation of various other chemical compounds. Its reactivity and the presence of fluorine and trifluoromethyl groups make it a versatile tool in the synthesis of target molecules, contributing to the advancement of chemical research and the development of new materials and products.

InChI:InChI=1/C8H6F4O/c9-7-3-6(8(10,11)12)2-1-5(7)4-13/h1-3,13H,4H2

Upstream product

• 115029-24-8 2-fluoro-4-(trifluoromethyl)benzoic acid 
• 89763-93-9 2-Fluoro-4-(trifluoromethyl)benzaldehyde 

Downstream Products

• 89763-93-9 2-Fluoro-4-(trifluoromethyl)benzaldehyde 
• 438046-84-5 Piperazine-1-carbothioic acid S-(2-fluoro-4-trifluoromethyl-benzyl)ester hydrochloride 
• 1000339-60-5 2-fluoro-4-trifluoromethylbenzyl chloride 
• 478373-86-3 2-{4'-Methoxy-3'-[(2-fluoro-4-trifluoromethylbenzyloxycarbonylamino)methyl]biphenyl-3-yl}propionic acid 
• 478373-56-7 {4'-Ethoxy-3'-[(2-fluoro-4-trifluoromethylbenzyloxycarbonylamino)methyl]biphenyl-3-yl}acetic acid 
• 478373-36-3 {4'-Methoxy-3'-[(2-fluoro-4-trifluoromethylbenzyloxycarbonylamino)methyl]biphenyl-3-yl}acetic acid 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUND

The present invention provides a compound having an MAGL inhibitory action, and useful as an agent for the prophylaxis or treatment of neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, glaucoma, multiple sclerosis etc.), anxiety disorder, pains (e.g., inflammatory pain, cancerous pain, neurogenic pain etc.), epilepsy, depression and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.

Efficient methods for the synthesis of arylacetonitriles

Various approaches to [2-fluoro-4-(trifluoromethyl)phenyl]acetonitrile were investigated. Two of these methods were selected and applied to a variety of electron-deficient substrates, thereby expanding the scopes of the procedures.

Vanilloid receptor ligands and their use in treatments

Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.