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19730-99-5

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19730-99-5 Usage

General Description

2-(Pyridin-3-yl)acetic acid hydrazide is a chemical compound with the molecular formula C8H9N3O. It is a hydrazide derivative of 2-(pyridin-3-yl)acetic acid, and it is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 2-(PYRIDIN-3-YL)ACETIC ACID HYDRAZIDE has been studied for its potential biological activities, including its use as a ligand in metal coordination chemistry. It is also being investigated for its potential as an antitumor and antiviral agent, making it of interest in drug discovery research. Additionally, 2-(pyridin-3-yl)acetic acid hydrazide has been examined for its potential to inhibit the growth of certain types of bacteria and fungi, making it of interest for applications in the field of antimicrobial agents. Overall, this chemical compound has versatile potential applications in various areas of research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 19730-99-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,7,3 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 19730-99:
(7*1)+(6*9)+(5*7)+(4*3)+(3*0)+(2*9)+(1*9)=135
135 % 10 = 5
So 19730-99-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H9N3O/c8-10-7(11)4-6-2-1-3-9-5-6/h1-3,5H,4,8H2,(H,10,11)

19730-99-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(PYRIDIN-3-YL)ACETIC ACID HYDRAZIDE

1.2 Other means of identification

Product number -
Other names 2-pyridin-3-ylacetic hydrazide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19730-99-5 SDS

19730-99-5Relevant articles and documents

Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S-Component of the Energy-Coupling Factor Transporter for Thiamine

Monjas, Leticia,Swier, Lotteke J. Y. M.,Setyawati, Inda,Slotboom, Dirk J.,Hirsch, Anna K. H.

supporting information, p. 1693 - 1696 (2017/10/27)

We applied dynamic combinatorial chemistry (DCC) to identify ligands of ThiT, the S-component of the energy-coupling factor (ECF) transporter for thiamine in Lactococcus lactis. We used a pre-equilibrated dynamic combinatorial library (DCL) and saturation-transfer difference (STD) NMR spectroscopy to identify ligands of ThiT. This is the first report in which DCC is used for fragment growing to an ill-defined pocket, and one of the first reports for its application with an integral membrane protein as target.

Novel spiropiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 1′-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-5-(trifluoromethyl)-3,4-dihydrospiro[chromene-2,4′-piperidine]

Uto, Yoshikazu,Kiyotsuka, Yohei,Ueno, Yuko,Miyazawa, Yuriko,Kurata, Hitoshi,Ogata, Tsuneaki,Deguchi, Tsuneo,Yamada, Makiko,Watanabe, Nobuaki,Konishi, Masahiro,Kurikawa, Nobuya,Takagi, Toshiyuki,Wakimoto, Satoko,Kono, Keita,Ohsumi, Jun

scheme or table, p. 746 - 754 (2010/06/11)

Cyclization of the benzoylpiperidine in lead compound 2 generated a series of novel and highly potent spiropiperidine-based stearoyl-CoA desaturase (SCD)-1 inhibitors. Among them, 1′-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-5-(trifluoromethyl)-3,4-dihydrospiro[chromene-2,4′-piperidine] (19) demonstrated the most powerful inhibitory activity against SCD-1, not only in vitro but also in vivo (C57BL/6 J mice). With regard to the pharmacological evaluation, 19 showed powerful reduction of the desaturation index in the plasma of C57BL/6 J mice on a non-fat diet after a 7-day oral administration (q.d.) without causing notable abnormalities in the eyes or skin up to the highest dose (3 mg/kg) in our preliminary analysis.

NAPHTHYRIDINE INTEGRASE INHIBITORS

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Page 88, (2010/02/09)

The present invention features compounds that are HIV integrase inhibitors and therefore are useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.

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