19733-96-1

Basic information

• Product Name: 2-(6-methylpyridin-3-yl)acetic acid
• Synonyms: 2-(6-methylpyridin-3-yl)acetic acid;6-Methyl-3-pyridineacetic acid;2-(6-Methylpyridin-3-yl)
• CAS NO: 19733-96-1
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151
• Mol File: 19733-96-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 73-74 °C
• Boiling Point: 298.721°C at 760 mmHg
• Flash Point: 134.462°C
• Appearance: /
• Density: 1.196g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.55
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 3.68±0.10(Predicted)
• CAS DataBase Reference: 2-(6-methylpyridin-3-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(6-methylpyridin-3-yl)acetic acid(19733-96-1)
• EPA Substance Registry System: 2-(6-methylpyridin-3-yl)acetic acid(19733-96-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 19733-96-1(Hazardous Substances Data)

Usage

General Description

2-(6-methylpyridin-3-yl)acetic acid is a chemical compound with the molecular formula C9H9NO2. It belongs to the class of organic compounds known as phenylacetic acids, which are compounds containing a phenylacetic acid moiety. 2-(6-methylpyridin-3-yl)acetic acid is also known by the names 3-(2-(6-methylpyridin-3-yl)acetamido)benzoic acid and N-(2-carboxyethyl)picolinamide. 2-(6-methylpyridin-3-yl)acetic acid is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and active pharmaceutical ingredients. It is also used in research and development of new drugs and pharmaceuticals.

InChI:InChI=1/C8H9NO2/c1-6-2-3-7(5-9-6)4-8(10)11/h2-3,5H,4H2,1H3,(H,10,11)

Upstream product

• 36357-38-7 1-(6-methyl-pyridin-3-yl)-ethanone 
• 3430-13-5 5-bromo-2-methylpyridine 
• 5470-70-2 Methyl 6-methylnicotinate 
• 90610-06-3 (6-methyl-pyridin-3-yl)-acetic acid methyl ester 
• 19733-95-0 4-[(6-methyl-pyridin-3-yl)-thioacetyl]-morpholine 

Downstream Products

• 1229621-59-3 N-(4-methylphenyl)-2-(6-methylpyridin-3-yl)acetamide 
• 21241-10-1 4-methyl-N-(2-(6-methylpyridin-3-yl)ethyl)aniline 
• 21241-09-8 4-methyl-N-[2-(6-methylpyridin-3-yl)ethyl]-N-nitrosoaniline 
• 100189-17-1 2-(6-methylpyridin-3-yl) ethan-1-ol 
• 1229621-60-6 N'-(1-methyl-piperidin-4-ylidene)-N-[2-(6-methyl-pyridin-3-yl)-ethyl]-N-p-tolyl-hydrazine 
• 21241-08-7 2-methyl-5-{2-[1-(4-methylphenyl)hydrazinyl]ethyl}pyridine 
• 3613-73-8 dimebon 
• 91843-27-5 ethyl (6-methylpyridin-3-yl)acetate 

Relevant articles and documents

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TETRAAZA-CYCLOPENTA[A]INDENYL DERIVATIVES

The present invention provides compounds of Formula (I) as M1 receptor positive allosteric modulators for the treatment of diseases mediated by the muscarinic M1 mediator.

SUSTAINED RELEASE COMPOSITION CONTAINING TETRAHYDROPYRIDO Y4, 3-b¨INDOLE DERIVATIVE AND PREPARATION METHOD OF DERIVATIVE

The present invention relates to a sustained-release composition containing 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole or a pharmaceutically acceptable salt thereof as an active ingredient, preparation thereof and the compound. The composition is suitable for oral administration by one time per day, and achieves the peak plasma concentration at 1.0 to 3 hours after oral administration. The composition is suitable for manufacturing a medicament for treatment of cognitive dysfunction syndrome, Alzheimer's disease, Parkinson's disease, Huntington's disease, or senile dementia.