197358-41-1

Upstream product

• 197358-37-5 (S)-2-Benzyloxycarbonylamino-3-[2-((S)-4-methoxycarbonylmethyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino]-propionic acid tert-butyl ester 
• 197358-35-3 (4-methoxycarbonylmethyl-2,5-dioxo-imidazolidin-1-yl)-acetic acid tert-butyl ester 
• 197358-36-4 ((S)-4-Methoxycarbonylmethyl-2,5-dioxo-imidazolidin-1-yl)-acetic acid 
• 152212-45-8 (S)-methyl 2-(2,5-dioxoimidazolidin-4-yl)acetate 
• 26184-53-2 ((S)-2,5-Dioxo-imidazolidin-4-yl)-acetic acid 
• 5805-57-2 2-Aminomethylbenzimidazole 
• 197358-38-6 (S)-2-Benzyloxycarbonylamino-3-[2-((S)-4-carboxymethyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino]-propionic acid tert-butyl ester 

Relevant academic research and scientific papers

RGD mimetics containing a central hydantoin scaffold: α(v)β3 vs α(IIb)β3 selectivity requirements

The synthesis of a series of RGD mimetic α(v)β3 antagonists containing a hydantoin scaffold is shown. The results demonstrate some of the structural requirements for the design of selective α(v)β3 antagonists (vs α(IIb)β3)