197367-75-2

Basic information

• Product Name: 7-Oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid
• Synonyms: 7-Oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid;4,7-dihydro-7-oxo-Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid
• CAS NO: 197367-75-2
• Molecular Formula: C₇H₅N₃O₃
• Molecular Weight: 179.135
• Mol File: 197367-75-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 402.362°C at 760 mmHg
• Flash Point: 197.141°C
• Appearance: /
• Density: 1.786g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.786
• PKA: 5.01±0.20(Predicted)
• CAS DataBase Reference: 7-Oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid(197367-75-2)
• EPA Substance Registry System: 7-Oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid(197367-75-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 197367-75-2(Hazardous Substances Data)

Usage

General Description

7-Oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid is a heterocyclic compound with the chemical formula C6H4N4O3. It is a pyrazolopyrimidine derivative that is commonly used as an intermediate in the synthesis of pharmaceutical compounds. 7-Oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid is known for its potential biological activities, including anti-inflammatory and anti-cancer properties. It is also used as a building block in the preparation of various pharmacologically active compounds. Overall, 7-Oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid plays a crucial role in the development of new drugs and pharmaceutical agents.

InChI:InChI=1/C7H5N3O3/c11-6-4(7(12)13)3-8-5-1-2-9-10(5)6/h1-3,8H,(H,12,13)

Upstream product

• 29274-17-7 diethyl 2-((1H-pyrazol-5-ylamino)methylene)malonate 
• 29274-18-8 ethyl 7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate 

Downstream Products

• 29274-23-5 4,7-dihydropyrazolo<1,5-a>pyrimidin-7-one 
• 877173-84-7 3-bromo-7-chloropyrazolo[1,5-a]pyrimidine 
• 58347-49-2 7-chloropyrazolo[1,5-a]pyrirnidine 
• 1161024-91-4 N-(2,4-di-tert-butyl-5-hydroxyphenyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide 

Relevant articles and documents

Acid Derivatives of Pyrazolo[1,5-a]pyrimidine as Aldose Reductase Differential Inhibitors

Aldose reductase (AKR1B1), the key enzyme of the polyol pathway, plays a crucial role in the development of long-term complications affecting diabetic patients. Nevertheless, the expedience of inhibiting this enzyme to treat diabetic complications has fai

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof of formula (I), including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention