19748-58-4Relevant academic research and scientific papers
17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS FOR THE TREATMENT OF HORMONE-RELATED DISEASES
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Page/Page column 29-30, (2011/04/14)
The invention relates to 17beta-hydroxysteroid dehydrogenase type 1 (17betaHSD1) inhibitors, the preparation thereof and the use thereof for the treatment and prophylaxis of hormone-related, especially estrogen-related or androgen-related, diseases.
Rapid synthesis of 2,5-disubstituted 1,3,4-oxadiazoles under microwave irradiation
Bentiss, Fouad,Lagrenee, Michel,Barbry, Didier
, p. 935 - 938 (2007/10/03)
A number of symmetrically 2,5-disubstituted 1,3,4-oxadiazoles are quickly prepared by the reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid and phosphorus pentoxide under microwave irradiation.
A new synthesis of symmetrical 2,5-disubstituted 1,3,4- oxadiazoles
Bentiss, Fouad,Lagrenee, Michel
, p. 1029 - 1032 (2007/10/03)
Several new 2,5-disubstituted 1,3,4-oxadiazoles have been synthesized in good yields by reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid, phosphorus pentoxide and, in general, with addition of phosphorus oxychloride to the reaction mixture. The structures of new oxadiazoles derivatives were confirmed by analytical and spectral data.
