1975-53-7

Usage

Uses

Used in Pharmaceutical Industry:
4-Cyano-2-methylbenzoic acid is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its reactivity and structural features make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Cyano-2-methylbenzoic acid is employed as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its role as an intermediate allows for the creation of effective and targeted agricultural products.
Used in Dye Industry:
4-Cyano-2-methylbenzoic acid is used as a building block in the synthesis of dyes, contributing to the development of a wide range of colorants for various applications, including textiles, plastics, and printing inks.
Used in Chemical Reactions:
Due to its enhanced reactivity, 4-Cyano-2-methylbenzoic acid is utilized in various chemical reactions, serving as a key component in the synthesis of different organic compounds and materials.

Upstream product

• 55984-93-5 2-methyl-1,4-dicyanobenzene 
• 124-38-9 carbon dioxide 
• 41963-20-6 4-bromo-3-methylbenzonirtile 
• 103261-67-2 4-cyano-2-methylbenzoic acid methyl ester 
• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 
• 68837-59-2 4-bromo-2-methylbenzoic acid 
• 220389-17-3 4-cyano-2-methyl-benzoic acid ethyl ester 

Downstream Products

• 103261-67-2 4-cyano-2-methylbenzoic acid methyl ester 
• 99357-97-8 4-carbamoyl-2-methylbenzoic acid 
• 744200-39-3 3-Methyl-4-(3-methyl-4,10-dihydro-3H-2,3,4,9-tetraazabenzo[f]azulene-9-carbonyl)-benzonitrile 
• 1161274-19-6 4-cyano-2-methylbenzoyl chloride 
• 1208330-99-7 ethyl 3-(2-(4-carbamoyl-2-methylphenyl)-1-(4-chloro-2-methoxyphenyl)-1H-pyrrol-3-yl)propanoate 
• 1208330-97-5 (E)-ethyl 3-(2-(4-carbamoyl-2-methylphenyl)-1-(4-chloro-2-methoxyphenyl)-1H-pyrrol-3-yl)acrylate 
• 1208330-95-3 4-(1-(4-chloro-2-methoxyphenyl)-3-formyl-1H-pyrrol-2-yl)-3-methylbenzamide 
• 1208330-93-1 4-(1-(4-chloro-2-methoxyphenyl)-3-(hydroxymethyl)-1H-pyrrol-2-yl)-3-methylbenzamide 
• 1208330-91-9 ethyl 2-(4-carbamoyl-2-methylphenyl)-1-(4-chloro-2-methoxyphenyl)-1H-pyrrole-3-carboxylate 
• 1208330-89-5 ethyl 1-(4-chloro-2-methoxyphenyl)-2-(4-cyano-2-methylphenyl)-1H-pyrrole-3-carboxylate 
• 1208331-50-3 ethyl 2-(4-cyano-2-methylbenzoyl)-4-oxobutanoate 
• 1208331-48-9 ethyl 2-(4-cyano-2-methylbenzoyl)pent-4-enoate 
• 1208331-46-7 ethyl 3-(4-cyano-2-methylphenyl)-3-oxopropanoate 
• 1208331-13-8 C₂₅H₂₁N₃O₃S 

Relevant academic research and scientific papers

Heteroarylacetic phenylbenzamide, composition and method of use (by machine translation)

Provided are certain heteroaryl benzamides, compositions, and methods of their manufacture and use.

Structure-activity relationships of pyrrole based S-nitrosoglutathione reductase inhibitors: Pyrrole regioisomers and propionic acid replacement

S-Nitrosoglutathione reductase (GSNOR) is a member of the alcohol dehydrogenase family (ADH) that regulates the levels of S-nitrosothiols (SNOs) through catabolism of S-nitrosoglutathione (GSNO). GSNO and SNOs are implicated in the pathogenesis of many diseases including those in respiratory, cardiovascular, and gastrointestinal systems. The pyrrole based N6022 was recently identified as a potent, selective, reversible, and efficacious GSNOR inhibitor which is currently undergoing clinical development. We describe here the synthesis and structure-activity relationships (SAR) of novel pyrrole based analogues of N6022 focusing on scaffold modification and propionic acid replacement. We identified equally potent and novel GSNOR inhibitors having pyrrole regioisomers as scaffolds using a structure based approach.

NOVEL FIVE-MEMBERED RING COMPOUND

Disclosed is a five-membered ring compound represented by formula (1) or a pharmaceutically acceptable salt thereof. The compound inhibits infiltration of leukocytes including eosinophils and lymphocytes, and is effective as a drug for treating various inflammations. The compound is highly safe and can be administered for a long period. A pharmaceutical product containing the five-membered ring compound or a pharmaceutically acceptable salt thereof is also disclosed. (In the formula, R1 represents a halogen atom or a phenyl group which may be substituted by a C1-C3 alkyl group or a C1-C3 alkoxy group; R2 represents a C1-C3 alkylene group which may be substituted by a C1-C3 alkyl group or a carbonyl group; R3 represents a C1-C3 alkyl group; R4 and R5 independently represent a hydrogen atom or a C1-C3 alkyl group, or -N(R4)R5 may represent a morpholino group which may be substituted by a C1-C3 alkyl group; Y2 represents a C2-C4 alkylene group; and R6 represents a hydrogen atom, a halogen atom, a C1-C3 alkyl group or a C1-C3 alkoxy group.)

INSECTICIDAL COMPOUNDS

The present invention relates to bis-amide derivatives of formula (I), to processes and intermediates for preparing them, to methods of using them to control insect, acarine, nematode and mollusc pests, and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them.

NEW 2-AMIDOTHIADIAZOLE DERIVATIVES

New 2-amidothiadiazole derivatives having the chemical structure of formula (I) or pharmaceutically acceptable salts or N-oxides thereof as agonists of S1P1 receptors.

INSECTICIDAL COMPOUNDS

A compound of formula (I) wherein A1, A2, A3, A4, G1, G2, R1, R2, L, Q1, and Q2 are as defined in claim 1; or a salt or N- oxide thereof. Furthermore, the present invention relates to processes and intermediates for preparing compounds of formula (I), to insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control insect, acarine, mollusc and nematode pests.

4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL

The present invention relates to bis-amide derivatives of formula (I), to processes and intermediates for preparing them,to methods of using them to control insect, acarine, nematode and mollusc pests,and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them.

INSECTICIDAL COMPOUNDS

A compound of formula (I): wherein A1, A2, A3, A4, G1, R1, R2, R3 and R4 are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present i

TROPANE COMPOUNDS

A compound according to Formula I or II: (I) or (II) wherein R1, R1b, R2, L1, and L2 and L2b are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.

HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS

The invention concerns compounds according to general formulae 1, wherein G1 is an amine. Compounds according to the invention are vasopressin V2 receptor agonists. Pharmaceutical compositions of the compounds are useful as antidiuretic agents.