1975-54-8Relevant articles and documents
Regioselective Hydrolysis of Aromatic Dinitriles Using a Whole Cell Catalyst
Crosby, John,Moilliet, Jock,Parratt, Julian S.,Turner, Nicolas J.
, p. 1679 - 1688 (2007/10/02)
A series of aromatic dinitriles have been examined as substrates for an immobilised whole cell Rhodococcus sp. that catalyses the hydrolysis of nitriles to amides and/or carboxylic acids.The fluorinated aromatic dinitriles 48 and 49 were regioselectively hydrolysed to the corresponding cyano amides 48a and 49a whereas the non-fluorinated analogues 41-44 were converted to cyano acids but with poorer regioselectivity.