197504-70-4

Upstream product

• 4463-33-6 1,2-dimethoxy-3-methylbenzene 
• 197504-68-0 1-(3,4-dimethoxy-2-methylphenyl)propan-2-yl acetate 
• 197504-67-9 1-(3,4-dimethoxy-2-methylphenyl)propan-2-ol 
• 74866-17-4 3,4-dimethoxy-2-methyl-1-bromobenzene 
• 197504-69-1 1-(3,4-dimethoxy-2-methyl-6-nitrophenyl)propan-2-yl acetate 

Downstream Products

• 937811-11-5 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylacetyl)-9H-carbazol-1-yl]propan-2-yl acetate 
• 207505-90-6 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylmethyl)-9H-carbazol-1-yl]propan-2-yl acetate 
• 207505-91-7 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylmethyl)(9H-carbazol-1-yl)]propan-2-ol 

Relevant academic research and scientific papers

Transition metals in organic synthesis, part 84.1 application of iron- and nickel-mediated coupling reactions to the total synthesis of the neuronal cell protecting substance (±)-carquinostatin A

Using iron- and nickel-mediated coupling reactions as key steps a convergent and highly efficient total synthesis of the potent neuronal cell protecting alkaloid (±)-carquinostatin A has been accomplished.

Transition Metal Complexes in Organic Synthesis, Part 39. First Total Synthesis of the Potent Neuronal Cell Protecting Substance (±)-Carquinostatin a via Iron- and Nickel-Mediated Coupling Reactions

The first total synthesis of the potent neuronal cell protecting carbazole alkaloid (±)-carquinostatin A was achieved by using an iron-mediated construction of the carbazole framework and a regioselective nickel-mediated prenylation as the key-steps.