197585-42-5 Usage
General Description
1-(Methoxycarbonyl)piperidine-4-carboxylic acid is a chemical compound with the molecular formula C10H17NO4. It is a piperidine derivative that contains a piperidine ring with a carboxylic acid group and a methoxycarbonyl moiety. 1-(Methoxycarbonyl)piperidine-4-carboxylic acid is a white solid that is soluble in organic solvents and is commonly used in the synthesis of pharmaceuticals and agrochemicals. It has the potential to be used as a building block for the preparation of various bioactive compounds and is also of interest in the development of new drugs. Its structure and properties make it a valuable reagent in organic chemistry research and drug discovery efforts.
Check Digit Verification of cas no
The CAS Registry Mumber 197585-42-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,5,8 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 197585-42:
(8*1)+(7*9)+(6*7)+(5*5)+(4*8)+(3*5)+(2*4)+(1*2)=195
195 % 10 = 5
So 197585-42-5 is a valid CAS Registry Number.
197585-42-5Relevant articles and documents
Beyond organic solvents: synthesis of a 5-HT4receptor agonist in water
Bailey, J. Daniel,Helbling, Edward,Mankar, Amey,Stirling, Matthew,Hicks, Fred,Leahy, David K.
, p. 788 - 795 (2021)
Reducing or eliminating organic solvent use in pharmaceutical manufacturing is perhaps the most effective way to reduce the environmental, health, and safety impacts of drug substance manufacturing. With this in mind, we have developed a process to manufacture an investigational 5-HT4receptor agonist that is conducted almost entirely in water, including multiple controlled isolations. Key transformations carried out in aqueous media include a benzimidazole cyclization, amide bond formation, reductive amination, and a selective oxidation of an aliphatic alcohol. Compared to the first-generation manufacturing process using organic solvents, the aqueous process described here uses 77% less material inputs, 94% less organic solvent, and, surprisingly, 48% less water, while improving overall yield from 35% to 56%.
