75250-59-8Relevant academic research and scientific papers
Synthesis of functionalized nitrogen heterocycles by radical decarboxylation of β- and γ-amino acids
Boto, Alicia,Hernandez, Rosendo,De Leon, Yolanda,Murguia, Jose R.,Rodriguez-Afonso, Abigail
, p. 673 - 682 (2007/10/03)
Iodinated or oxygenated nitrogen heterocycles are obtained by radical decarboxylation of β- and γ-amino acids. This mild, versatile reaction is applied to the synthesis of bioactive products, such as 4-arylpiperidines, hydroxylated piperidines, and new antifungal agents.
Stereoselective Intramolecular Aminocarbonylation of 3-Hydroxypent-4-enylamides Catalyzed by Palladium
Tamaru, Yoshinao,Kobayashi, Takuji,Kawamura, Shin-ichi,Ochiai, Hirofumi,Yoshida, Zen-ichi
, p. 4479 - 4482 (2007/10/02)
The urethanes and tosamides of 3-Hydroxypent-4-enylamine and its C1-C4 substituted derivatives undergo the palladium catalyzed intramolecular aminocarbonylation (0.1 equiv of PdCl2, 3.0 equiv of CuCl2, 3.0 equiv of NaOAc i
Organic Tellurium and Selenium Chemistry. Reduction of Tellurides, Selenides, and Selenoacetals with Triphenyltin Hydride
Clive, Derrick L. J.,Chittattu, Gim J.,Farina, Vittorio,Kiel, William A.,Menchen, Steven M.,et al.
, p. 4438 - 4447 (2007/10/02)
Preparative and mechanistic details are described for the conversion of selenides into hydrocarbons RH> by heating with triphenyltin hydride at about 120 deg C.The process has been extended to selenoacetals in a form that constitutes a reduction methods for carbonyl compounds RR'C(SePh)2 -> RR'CH2>.Selective reduction of selenoacetals in the presence of thioacetals is possible.Cold-labeled species can be prepared by using triphenyltin deuteride.Tellurides are available easily without problems arising from exposure to air provided that the work is done in a photographic darkroom equipped with a red safety light.These tellurides, as well as the corresponding dichlorides , are reduced under very mild conditions (25-80 deg C) by triphenyltin hydride.The selenium- and tellurium-based chemistry has been used for the unusual process of reducing an epoxide in the presence of a ketone carbonyl.
