197590-75-3

Upstream product

• 54828-68-1 (R)-p-tolyl vinyl sulfoxide 
• 187030-98-4 1-methyl-4-phenyl-3-pyridiniumolate 
• 27328-17-2 (S)-(-)-p-tolyl vinyl sulfoxide 

Downstream Products

• 208989-31-5 (1S,5S,6R)-2-acetoxy-N-methyl-3-phenyl-6β-(p-tolylthio)-8-azabicyclo<3.2.1>oct-3-ene 
• 197590-86-6 (1S,4S,5S,6R)-4-Butyl-8-methyl-3-phenyl-6-p-tolylsulfanyl-8-aza-bicyclo[3.2.1]oct-2-ene 
• 197590-79-7 (1S,5S,7R)-N-methyl-3-phenyl-2β-n-propyl-7β-(p-tolylthio)-8-azabicyclo<3.2.1>oct-3-ene 
• 208989-56-4 (1S,5S,6R)-8-Methyl-3-phenyl-6-((R)-toluene-4-sulfinyl)-8-aza-bicyclo[3.2.1]oct-3-en-2-ol 

Relevant academic research and scientific papers

Tropane derivatives and method for their synthesis

A compound of formula (I) wherein R1-R6have any of the values defined in the specification are described, as well as pharmaceutical compositions comprising a compound of formula (I), and methods for preparing and using compounds of f

Synthesis and biological properties of new 2β-alkyl- and 2β-aryl-3- (substituted phenyl)tropane derivatives: Stereochemical effect of C-3 on affinity and selectivity for neuronal dopamine and serotonin transporters

In our efforts to identify molecules that might act as cocaine antagonists or cocaine partial agonists, we have been involved in efforts to further elucidate the nature of cocaine's binding to the dopamine transporter (DAT) through strategic modifications

An enantioselective synthesis of 2-alkyl-3-phenyltropanes by an asymmetric 1,3-dipolar cycloaddition reaction

A method for gaining access to 2-alkyl-3-phenyl-substituted tropanes using the chiral dipolarophile (R)-p-tolyl vinyl sulfoxide in the asymmetric 1,3-dipolar cycloaddition reaction with the oxidopyridinium betaine 4 is described.