197657-32-2Relevant academic research and scientific papers
α-bisabolol β-D-fucopyranoside as a potential modulator of β-amyloid peptide induced neurotoxicity: An in vitro & in silico study
Jeyakumar, Mahalingam,Sathya, Sethuraman,Gandhi, Soniya,Tharra, Prabhakarrao,Suryanarayanan, Venkatesan,Singh, Sanjeev Kumar,Baire, Beeraiah,Pandima Devi, Kasi
, (2019)
Alzheimer's disease (AD) is a multifaceted neurodegenerative disorder affecting the elderly people. For the AD treatment, there is inefficiency in the existing medication, as these drugs reduce only the symptoms of the disease. Since multiple pathological
Continuous nonradioactive method for screening trypanosomal transsialidase activity and its inhibitors
Sartor, Paula A.,Agusti, Rosalia,Leguizamon, Maria S.,Campetella, Oscar,de Lederkremer, Rosa M.
experimental part, p. 982 - 990 (2010/12/25)
Trypanosoma cruzi, the agent of American trypanosomiasis is unable to synthesize sialic acid (SA). Instead of using the corresponding nucleotide sugar as donor of the monosaccharide, the transfer occurs from α-2,3-linked SA in the host sialoglycoconjugate
Synthesis and cytotoxicity evaluation of natural α-bisabolol β-d-fucopyranoside and analogues
Piochon, Marianne,Legault, Jean,Gauthier, Charles,Pichette, Andre
experimental part, p. 228 - 236 (2009/09/05)
α-Bisabolol β-d-fucopyranoside, a cytotoxic naturally occurring compound, was efficiently synthesized along with five other α-bisabolol glycosides (β-d-glucoside, β-d-galactoside, α-d-mannoside, β-d-xyloside and α-l-rhamnoside). Glycosidation of α-bisabol
Parasite glycoconjugates. Part 11: Preparation of phosphodisaccharide synthetic probes, substrate analogues for the elongating α-D-mannopyranosylphosphate transferase in the Leishmania
Ross, Andrew J.,Ivanova, Irina A.,Ferguson, Michael A.J.,Nikolaev, Andrei V.
, p. 72 - 81 (2007/10/03)
The preparation of phosphodisaccharide synthetic probes was presented. The Koenings-Knorr and trichloroacetimidate methods for the glycosylation reactions, Sn2 nucleophilic displacement of a triflic ester for epimerization and the glycosyl hydr
Synthesis of 4-nitrophenyl β-D-fucofuranoside and β-D-fucofuranosyl-(1 → 3)-D-mannopyranose: Modified substrates for studies on catalytic requirements of β-D-galactofuranosidase
Chiocconi, Alejandro,Marino, Carla,De Lederkremer, Rosa M.
, p. 7 - 13 (2007/10/03)
Syntheses of 4-nitrophenyl β-D-fucofuranoside (6) and β-D- fucofuranosyl-(1 → 3)-D-mannopyranose (10) are reported. These compounds, as analogues of galactofuranosides, were used for studying the influence of the hydroxyl group at C-6 in the interaction o
The synthesis of methyl-3-O-(β-D-fucopyranosyl)-β-D-quinovopyranoside and its 3′-O-, 2,3′-di-O-, and 2′,3′-di-O-methyl derivatives
Khatuntseva,Sherman,Shashkov,Dabrowski,Nifant'ev
, p. 205 - 210 (2007/10/03)
Methyl-3-O-(β-D-fucopyranosyl)-β-D-quinovopyranoside and its 3′-O-, 2,3′-di-O-, and 2′,3′-di-O-methyl derivatives were obtained by the regioselective Helferich glycosylation of methyl-2-O-benzyl-β-D-quinovopyranoside with the 2,3,4-tri-O-benzoyl-α-D-fucopyranosyl bromide followed by the methylation with diazomethane or methyl iodide.
