197663-22-2

Upstream product

• 507-09-5 tiolacetic acid 
• 197663-21-1 N-trichloroethoxycarbonyl-3-O-(3,4-di-O-acetyl-2-azido-2-deoxy-6-O-triphenylmethyl-α-D-galactopyranosyl)-L-serine benzyl ester 
• 197663-19-7 phenyl-2-azido-2-deoxy-1-thio-D-galactopyranoside 
• 84278-00-2 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose 
• 197663-20-0 phenyl-3,4-di-O-acetyl-2-azido-6-O-triphenylmethyl-2-deoxy-1-thio-D-galactopyranoside 
• 82911-81-7 benzyl N-(2,2,2-trichloroethoxycarbonyl)-L-serine 
• 914800-95-6 phenyl 2-azido-2-deoxy-1-thio-6-O-trityl-D-galactopyranoside 

Downstream Products

• 197663-25-5 O--(2->6)-O-(2-acetamido-3,4-di-O-acetyl-2-deoxy-α-D-galactopyranosyl)-(1->3)-N-(trichloroethoxycarbonyl)-L-serine-(N'-benzyloxycarbonylaminoethyl)... 
• 197663-24-4 O--(2->6)-O-(2-acetamido-3,4-di-O-acetyl-2-deoxy-α-D-galactopyranosyl)-(1->3)-N-(trichloroethoxycarbonyl)-L-serine benzyl ester 
• 197663-23-3 N-trichloroethoxycarbonyl-3-O-(2-acetamido-3,4-di-O-acetyl-2-deoxy-α-D-galactopyranosyl)-L-serine benzyl ester 

Relevant academic research and scientific papers

Synthesis of Tn, sialyl Tn and HIV-1-derived peptide antigen conjugates having a lipid a analog as an immunoadjuvant for synthetic vaccines

Conjugates (3-5) of Tn, sialyl Tn and HIV-1-derived peptide antigen with a N-tetradecanoyl L-serine-β-alanine-containing D-glucosamine derivative, structurally related to lipid A, as an immunoadjuvant for the development of totally synthetic vaccines against cancers or HIV were synthesized. The mitogenic activity of compounds 3, 4 and 5 was stronger than that of lipid A analogs (1, 2).

Synthesis of Tn, and sialyl Tn antigen-lipid a analog conjugates for synthetic vaccines

Conjugates of Tn and sialyl Tn antigen with N-teradecanoyl L-seryl-β- alanine-containing 9-glucosamine derivatives structurally related to lipid A as a immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers or HIV.