1977-11-3 Usage
Uses
Used in Pharmaceutical Industry:
Perlapine is used as an antipsychotic agent for its ability to block dopamine and serotonin receptors, which can help in managing the symptoms of psychotic disorders. Its action on these receptors contributes to its antipsychotic activity, making it a valuable compound in the development of treatments for conditions such as schizophrenia and bipolar disorder.
Used in Neuroscience Research:
As a novel agonist of hM3Dq, perlapine is used in neuroscience research to study the effects of activating this designer receptor exclusively activated by designer drugs (DREADD). This application allows researchers to investigate the role of hM3Dq in neuronal firing and potentially uncover new insights into the functioning of the human muscarinic acetylcholine M3 receptor and related neurological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1977-11-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1977-11:
(6*1)+(5*9)+(4*7)+(3*7)+(2*1)+(1*1)=103
103 % 10 = 3
So 1977-11-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H21N3/c1-21-10-12-22(13-11-21)19-17-8-4-2-6-15(17)14-16-7-3-5-9-18(16)20-19/h2-9H,10-14H2,1H3
1977-11-3Relevant academic research and scientific papers
PESTICIDAL DIBENZO(HETERO)AZEPINE DERIVATIVES
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Page 75, (2010/02/07)
Use of compounds of formula (I): wherein X is S, O, S=O, SO2, NRa, or CRbRc;R1,R2 are halogen, OH, SH, NH2, CN, NO2, alkyl, alkoxy, alkylamino, dialkylamino, alkylthio
Morphanthridines: Part III - A New Synthesis of 6-(4-Methyl-1-piperazinyl)-morphanthridine
Sinha, Ashok Kumar,Nizamuddin, S.
, p. 165 (2007/10/02)
6-(4-Methyl-1-piperazinyl)morphanthridine (V) has been prepared by a new route involving Beckmann rearrangement of anthron-oxime (II) with PPA followed by treatment of the resultant 5,6-dihydro-6-oxomorphanthridine (III) with PCl5 and then with N-methylpiperazine.
