1977-37-3Relevant academic research and scientific papers
EPR study of gamma irradiated DL-methionine sulfone single crystals
Karabulut, Bünyamin,Yildirim, Ilkay
, p. 186 - 189 (2015)
Electron paramagnetic resonance (EPR) study of gamma irradiated dl-2-amino-4-(Methylsulfonyl) butyric acid (dl-methionine sulfone, hereafter dl-ABA) single crystals and powder was performed at room temperature. It has been found that this compound indicates the existence of C.O2- and N.H2 radicals after γ-irradiation. While g and hyperfine splitting values for the N.H2 radical were observed, for the C.O2- radical, only the g factor was measured. The EPR spectra have shown that N.H2 radical has two groups each having two distinct sites and C.O2- radical has one site. The principal g and hyperfine values for all sites were analyzed.
Ultrasonically Dispersed Potassium in Organic Synthesis. Water-Acceleration in Reductive C-S Bond Cleavage Reactions
Chou, Ta-shue,Hung, Shao-Hwa,Peng, Man-Li,Lee, Shwu-Jiaun
, p. 3551 - 3554 (1991)
The slow addition of a pre-measured amount of water in THF can greatly enhance the UDP induced C-S bond cleavage reactions of cyclic sulfones.This reaction can be used in the synthesis of open chain sulfones with γ-, δ- or ε-deuteration.
Synthesis and oxidation catalysis of a Ti-substituted phosphotungstate, and identification of the active oxygen species
Takahashi, Eri,Kamata, Keigo,Kikukawa, Yuji,Sato, Sota,Suzuki, Kosuke,Yamaguchi, Kazuya,Mizuno, Noritaka
, p. 4778 - 4789 (2015/10/05)
In this paper, we report the synthesis of a Ti-substituted phosphotungstate, TBA6[(γ-PW10O36)2Ti4(μ-O)2(μ-OH)4] (I, TBA = tetra-n-butylammonium), and its application to H2O2-based oxidation. Firstly, an organic solvent-soluble dilacunary phosphotungstate precursor, TBA3[γ-PW10O34(H2O)2] (PW10), has been synthesized. By the reaction of PW10 and TiO(acac)2 (acac = acetylacetonate) in an organic medium (acetonitrile), I can be obtained. Compound I possesses a tetranuclear Ti core which can effectively activate H2O2 and shows high catalytic performance for several oxidation reactions, such as epoxidation of alkenes, oxygenation of sulfides, oxidative bromination of unsaturated compounds, and hydroxylation of anisole, giving the corresponding oxidation products with high efficiencies and selectivities. The catalytic performance of I is much superior to those of previously reported Ti-substituted polyoxometalates. In addition, I is highly durable during catalysis and can be reused several times while keeping its high catalytic performance. Furthermore, we have successfully isolated the truly catalytically active species for the present I-catalyzed oxidation, TBA6[(γ-PW10O36)2Ti4(μ-η2:η2-O2)4] (II), and its anion structure has been determined by X-ray crystallographic analysis. All of the four Ti2-μ-η2:η2-peroxo species in II are active for stoichiometric oxidation (without H2O2), and II is included in the catalytic cycle for I-catalyzed oxidation.
Disposition and metabolism of dipropyl disulphide in vivo in rat
Germain,Semon,Siess,Teyssier
, p. 87 - 97 (2008/09/17)
The metabolism of dipropyl disulphide (DPDS), a sulphur compound from onion, was investigated in vivo in the rat. A single dose (200 mg kg-1) was administered by gastric intubation and the time courses of DPDS and its metabolites were followed over 48 h by gas chromatography coupled with mass spectrometry in the stomach, intestine, liver, and blood. DPDS was detected in the stomach where it was transformed into propyl mercaptan, whereas the liver contained only traces of DPDS and none at all in the other examined organs. The metabolites methylpropyl sulphide, methylpropyl sulphoxide (MPSO), and methylpropyl sulphone (MPSO2) were sequentially formed in the liver. The route of elimination from the liver seemed to be mainly via the blood. The bile also participated in the excretory process, but only for MPSO2. The pharmacokinetic parameters were determined for all of the above compounds. Whereas the bioavailability of DPDS was very low (0.008 h mM), the areas under the curve were higher for the S-oxidized metabolites MPSO and MPSO2, i.e. 9.64 and 24.15 h mM, respectively. The half-lives for DPDS and its metabolites varied between 2.0 and 8.25 h, except for MPSO2, which had a half-life of 29.6 h. MPSO2 was the most abundant and persistent of these metabolites.
Niobium peroxo complexes with organic ligands as catalysts of organic sulfide oxidation in two-phase systems
Siukaeva,Fedorova,Aslanov,Tarakanova,Anisimov
, p. 289 - 291 (2007/10/03)
New niobium peroxo complexes with various ligands were prepared, and their activity as catalysts for the selective oxidation of organic sulfides with hydrogen peroxide was evaluated. Copyright
A mild and efficient procedure for the oxidation of organic sulfides to sulfones by use of urea-hydrogen peroxide/trifluoroacetic anhydride system
Balicki, Roman
, p. 2235 - 2239 (2007/10/03)
Selective, mild and safe oxidation of dialkyl-, diaryl- and alkyl-aryl sulfides to the corresponding sulfones was achieved by using of urea- H2O2/trifluoroacetic anhydride system.
New procedures for the oxidation of sulfides to sulfoxides and sulfones
Drabowicz, Jozef,Lyzwa, Piotr,Luczak, Jerzy,Mikolajczyk, Marian,Laur, Peter
, p. 425 - 426 (2007/10/03)
New reagents for the oxidation of sulfides to the corresponding sulfoxides and sulfones are presented.
CONVENIENT DESULFONYLATION REACTIONS OF CYCLIC SULFONES WITH ULTRASONICALLY DISPERSED POTASSIUM
Chou, Ta-shue,You, Mei-Li
, p. 4495 - 4498 (2007/10/02)
Ultrasonically dispersed potassium, generated in toluene with an ultrasonic cleaning bath, was found to be efficient and regioselective for desulfonylation of cyclic sulfones.
