1978-20-7

Basic information

• Product Name: 3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE
• Synonyms: 1,2-BIS(TRIFLUOROMETHYL)-4-NITROBENZENE;3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE;4-nitro-1,2-di(trifluoromethyl)benzene;3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE, 97% MIN.;4-Nitro-1,2-bis(trifluoromethyl)benzene;1,2-Bis(trifluoromethyl)-4-nitrobenzene, alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-4-nitro-o-xylene;3,4-Bis(trifluoromethyl)nitrobenzene AldrichCPR
• CAS NO: 1978-20-7
• Molecular Formula: C₈H₃F₆NO₂
• Molecular Weight: 259.11
• Product Categories: Benzene series;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 1978-20-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 23-25 °C
• Boiling Point: 103-104°C 18mm
• Flash Point: 80 °C
• Appearance: /
• Density: 1.539 g/cm³
• Vapor Pressure: 0.305mmHg at 25°C
• Refractive Index: 1.421
• CAS DataBase Reference: 3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE(1978-20-7)
• EPA Substance Registry System: 3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE(1978-20-7)

Safety Data

• Hazard Codes: T,Xi
• Statements: 36/37/38-36
• Safety Statements: 26-37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 1978-20-7(Hazardous Substances Data)

Usage

Uses

3,4-Bis(trifluoromethyl)nitrobenzene is used as reactant in the sythetic preparation of 4,5-bis(trifluoromethyl)benzimidazole.

InChI:InChI=1/C8H3F6NO2/c9-7(10,11)5-2-1-4(15(16)17)3-6(5)8(12,13)14/h1-3H

Upstream product

• 121-01-7 4-nitro-2-trifluoromethyl-aniline 
• 433-95-4 1,2-bis(trifluoromethyl)benzene 
• 610-27-5 4-nitrophthalic acid 
• 680-15-9 2,2-difluoro-2-(fluorosulfonyl)acetate 
• 400-75-9 1-iodo-4-nitro-2-(trifluoromethyl)benzene 
• 651-36-5 trichloromethyl-trifluoromethyl-benzene 
• 2741-57-3 o-dichloromethyltrichloromethylbenzene 
• 707-72-2 o-trifluoromethyl-α,α-dichlorotoluene 

Downstream Products

• 794-56-9 1-(trifluoroacetamido)-3,4-bis(trifluoromethyl)benzene 
• 2965-07-3 3,4-Bis(trifluoromethyl)aniline 
• 610-27-5 4-nitrophthalic acid 
• 1417658-11-7 N-(3,4-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide 

Relevant articles and documents

Discovery of Potent Antiallergic Agents Based on ano-Aminopyridinyl Alkynyl Scaffold

Effective therapeutic agents are highly desired for immune-mediated allergic diseases. Herein, we report the design, synthesis, and structure-activity relationship of ano-aminopyridinyl alkyne series as novel orally bioavailable antiallergic agents, which