707-72-2

Usage

Uses

Used in Pharmaceutical Industry:
2-(TRIFLUOROMETHYL)BENZAL CHLORIDE is used as a synthetic intermediate for the production of fine chemicals and active pharmaceutical ingredients. It is favored for its ability to undergo diverse chemical reactions, which is crucial for creating complex drug molecules.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(TRIFLUOROMETHYL)BENZAL CHLORIDE serves as a key intermediate, contributing to the development of effective crop protection agents and other agricultural products.
Used in Organic Synthesis:
2-(TRIFLUOROMETHYL)BENZAL CHLORIDE is utilized as a versatile building block in organic synthesis, enabling the introduction of the trifluoromethyl group into a broad spectrum of compounds, enhancing their properties and reactivity.
Used in Material Science:
2-(TRIFLUOROMETHYL)BENZAL CHLORIDE is employed in the field of material science as a component in the development of innovative functional materials. Its unique properties contribute to the creation of materials with distinct characteristics for specialized applications.

InChI:InChI=1/C8H5Cl2F3/c9-7(10)5-3-1-2-4-6(5)8(11,12)13/h1-4,7H

Upstream product

• 651-36-5 trichloromethyl-trifluoromethyl-benzene 
• 2741-57-3 o-dichloromethyltrichloromethylbenzene 
• 95-47-6 o-xylene 

Downstream Products

• 651-36-5 trichloromethyl-trifluoromethyl-benzene 
• 88-16-4 1-chloro-2-(trifluoromethyl)benzene 
• 610-27-5 4-nitrophthalic acid 
• 433-95-4 1,2-bis(trifluoromethyl)benzene 
• 603-11-2 3-nitrophthalic acid 
• 2965-07-3 3,4-Bis(trifluoromethyl)aniline 
• 1978-06-9 1,2-Bis(trifluoromethyl)-3-nitrobenzene 
• 1978-20-7 3,4-bis(trifluoromethyl)nitrobenzene 
• 3822-20-6 2,3-ditrifluoromethylaniline 
• 433-97-6 2-trifluoromethylbenzoic acid 
• 157229-44-2 o-trifluoromethyl-4-chloro-α,α-dichlorotoluene 
• 447-61-0 2-Trifluoromethylbenzaldehyde 
• 122947-75-5 2-dichloromethyl-5-nitrobenzotrifluoride 
• 320-43-4 4-chloro-2-(trifluoromethyl)benzaldehyde 

Relevant academic research and scientific papers

Synthetic method of o-trifluoromethyl benzoyl chloride

The invention discloses a synthesis method of o-trifluoromethyl benzoyl chloride, o-xylene is used as a starting raw material, the o-trifluoromethyl benzoyl chloride is synthesized through chlorination, fluorination, hydrolysis, acylating chlorination and rectification reaction in sequence, and the invention further provides ceramic balls, a modified TPU material and a fluorination auxiliary agent used in the synthesis method of the o-trifluoromethyl benzoyl chloride. According to the method, the low-toxicity color liquid o-xylene is adopted as the initial raw material, the reaction safety is high, and the yield of the target product o-trifluoromethyl benzoyl chloride is comprehensively improved by improving the utilization rate of chlorine and hydrogen fluoride and reducing by-products.

AN IMPROVED PROCESS FOR PREPARATION OF TRIFLUOROMETHYLBENZALDEHYDES AND INTERMEDIATES THEREOF

The present invention provides an in-situ process for preparation of a compound of formula 1 and intermediate thereof, These compounds are useful chemical intermediates for the production of pesticides and pharmaceutical products.

A O-trifluoro methyl process for the preparation of formaldehyde

The invention discloses a method for preparing o-trifluoromethyl benzaldehyde. The method for preparing the o-trifluoromethyl benzaldehyde, disclosed by the invention, comprises the following steps: in the presence of a catalyst, carrying out hydrolysis reaction on a mixture of o-trifluoromethyl methylbenzene bichloride, o-trifluoromethyl chloro-fluoro-methylbenzene and o-trifluoromethyl methylbenzene difluoride and water at the temperature of 80-150 DEG C to obtain, wherein the mass of the catalyst accounts for 0.01-10% of the mass of the mixture. The method disclosed by the invention is cheap and easily available in raw materials, low in cost, little in wastewater, low in energy consumption and simple in operation and can be suitable for industrial production. The structural formula of the o-trifluoromethyl benzaldehyde is shown in the specification.

REDUKTION VON BENZOTRICHLORIDEN ZU BENZALCHLORIDEN

Benzal chlorides are prepared from the corresponding benzotrichlorides by reduction with thiophenol in the presence of catalytic amounts of copper(I) bromide.