197846-05-2

Basic information

• Product Name: 2-Bromo-3-furoic acid
• Synonyms: 2-Bromo-3-furoic acid;2-Bromo-3-furoic acid 97%;2-bromo3-Furancarboxylic acid;2-Bromofuran-3-carboxylic acid, 2-Bromo-3-carboxyfuran;2-Bromofuran-3-carboxylic acid;2-Bromofuran-3-carboxylic acid 96%;2-Bromo-3-furoicacid97%
• CAS NO: 197846-05-2
• Molecular Formula: C₅H₃BrO₃
• Molecular Weight: 190.97952
• Mol File: 197846-05-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 160.5 °C
• Boiling Point: 273.5 °C at 760 mmHg
• Flash Point: 119.2 °C
• Appearance: /
• Density: 1.891 g/cm³
• Vapor Pressure: 0.00278mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: 2-8°C
• PKA: 3.57±0.20(Predicted)
• CAS DataBase Reference: 2-Bromo-3-furoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-3-furoic acid(197846-05-2)
• EPA Substance Registry System: 2-Bromo-3-furoic acid(197846-05-2)

Safety Data

• Hazard Codes: C,Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 197846-05-2(Hazardous Substances Data)

Usage

Uses

2-Bromo-3-furoic Acid is a reagent used in the synthesis of anti-muscarinic antagonists.

InChI:InChI=1/C5H3BrO3/c6-4-3(5(7)8)1-2-9-4/h1-2H,(H,7,8)

Upstream product

• 1710-13-0 dimethyl furan-2,4-dicarboxylate 
• 488-93-7 3-Furoic acid 

Downstream Products

• 1334394-42-1 4-[3-(Toluene-4-sulfonyloxymethyl)furan-2-yl]-piperidine-1-carboxylic Acid t-Butyl Ester 
• 197846-06-3 methyl 2-bromofuran-3-carboxylate 
• 197846-07-4 2-Bromo-furan-3-carboxylic acid phenylamide 
• 915707-69-6 2-bromofuran-3-carbonyl chloride 

Relevant articles and documents

Photostable Helical Polyfurans

This report describes the design and synthesis of a new class of polyfurans bearing ester side chains. The macromolecules can be synthesized using catalyst-transfer polycondensation, providing precise control over molecular weight and molecular weight distribution. Such obtained furan ester polymers are significantly more photostable than their alkyl analogues owing to the electron-withdrawing nature of the attached subunit. Most interestingly, they spontaneously fold into a compact π-stacked helix, yielding a complex multilayer cylindrical nanoparticle with a hollow, rigid, conjugated core composed of the polyfuran backbone and a soft, insulating outer layer formed by the ester side chains. The length of polymer side chains dictates the outer diameter of such nanoparticles, which for the hexyl ester groups used in the present study is equal to ～2.3 nm. The inner cavity of the conjugated core is lined with oxygen atoms, which set its effective diameter to 0.4 nm. Furthermore, installation of bulkier, branched chiral ester side chains on the repeat unit yields structures that, upon change of solvent, can reversibly transition between an ordered chiral helical folded and disordered unfolded state.