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197853-31-9

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  • Benzonitrile, 4-[[5-[[4-(3-chlorophenyl)-2-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl] methyl]-

    Cas No: 197853-31-9

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197853-31-9 Usage

Description

L 778,123 is a nitrofuran antibiotic with broad-spectrum activity against various Gram-positive and Gram-negative bacteria, as well as some protozoa. It inhibits bacterial DNA synthesis, leading to the death of the bacteria. Although its exact mechanism of action is not completely understood, L 778,123 is considered a promising antibiotic for clinical applications.

Uses

Used in Urinary Tract Infections:
L 778,123 is used as an antibiotic for treating urinary tract infections caused by susceptible bacteria. Its broad-spectrum activity makes it effective against a variety of bacteria responsible for these infections.
Used in Gastrointestinal Infections:
L 778,123 is used as an antibiotic for treating gastrointestinal infections, including those caused by both Gram-positive and Gram-negative bacteria. Its ability to target a wide range of bacteria contributes to its effectiveness in managing these infections.
Used in Skin Infections:
L 778,123 is used as an antibiotic for treating skin infections caused by susceptible bacteria. Its broad-spectrum activity allows it to address various types of skin infections effectively.
Used in Antibacterial Research:
L 778,123 is used as a research compound for studying the mechanisms of action and potential clinical applications of nitrofuran antibiotics. Its unique properties and broad-spectrum activity make it a valuable tool in the development of new antimicrobial agents.
Used in Drug Development:
L 778,123 is used as a lead compound in the development of new antibiotics with improved efficacy, safety, and resistance profiles. Its broad-spectrum activity and potential for clinical applications make it a promising candidate for further research and development in the pharmaceutical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 197853-31-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,8,5 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 197853-31:
(8*1)+(7*9)+(6*7)+(5*8)+(4*5)+(3*3)+(2*3)+(1*1)=189
189 % 10 = 9
So 197853-31-9 is a valid CAS Registry Number.

197853-31-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[(5-{[4-(3-Chlorophenyl)-2-oxo-1-piperazinyl]methyl}-1H-imidazo l-1-yl)methyl]benzonitrile

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:197853-31-9 SDS

197853-31-9Downstream Products

197853-31-9Relevant articles and documents

Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase

Dinsmore, Christopher J,Bergman, Jeffrey M,Wei, Donna D,Zartman,Davide, Joseph P,Greenberg, Ian B,Liu, Dongming,O'Neill, Timothy J,Gibbs, Jackson B,Koblan, Kenneth S,Kohl, Nancy E,Lobell, Robert B,Chen, I-Wu,McLoughlin, Debra A,Olah, Timothy V,Graham, Samuel L,Hartman, George D,Williams, Theresa M

, p. 537 - 540 (2007/10/03)

The evaluation of SAR associated with the insertion of carbonyl groups at various positions of N-arylpiperazinone farnesyltransferase inhibitors is described herein. 1-Aryl-2,3-diketopiperazine derivatives exhibited the best balance of potency and pharmac

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