198206-80-3Relevant academic research and scientific papers
A simple synthesis of the natural 2,5-dialkylresorcinol free radical scavenger antioxidant: Resorstatin
Combes, Sebastien,Finet, Jean-Pierre
, p. 3769 - 3778 (1997)
3,5-Dimethoxybenzoic acid 3 has been transformed into olivetol dimethyl ether 6 in three steps in 79% yield. Directed ortho-metallation-alkylation of 6, followed by boron tribromide demethylation resulted in a simple and inexpensive synthesis of resorstatin, in 70% overall yield from 3.
