198211-15-3

Usage

Uses

Used in Pharmaceutical Research and Synthesis:
(2R,6S)-1-benzyl-2,6-dimethylpiperidin-4-one is used as a key intermediate in the synthesis of biologically active molecules, given that piperidinones are common structural motifs in many pharmaceutical compounds.
Used in Organic Chemistry:
(2R,6S)-1-benzyl-2,6-dimethylpiperidin-4-one is utilized as a building block in organic chemistry for the development of novel chemical entities and the exploration of new reaction pathways.
Used in Drug Discovery:
(2R,6S)-1-benzyl-2,6-dimethylpiperidin-4-one is employed as a template in drug discovery for the design and optimization of new therapeutic agents, particularly due to the widespread study of piperidine-based compounds for their medicinal properties.

Upstream product

• 45717-87-1 2,6-dimethylpiperidin-4-one 
• 100-39-0 benzyl bromide 
• 542-05-2 acetonedicarboxylic acid 
• 75-07-0 acetaldehyde 
• 100-46-9 benzylamine 

Downstream Products

• 13200-35-6 (2S,6R)-2,6-dimethylpiperidin-4-one 
• 1005397-64-7 tert-butyl-cis-2,6-dimethyl-4-oxopiperidine-1-carboxylate 

Relevant academic research and scientific papers

CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are piperidine dione compounds having the following structure: wherein R1, R2, R3, R4, L, V, X, A, A′, a and m are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are piperidine dione compounds having the following structure: wherein R1, R2, R3, R4, L, V, X, a and m are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are piperidine dione compounds having the following structure: wherein RN, R1, R2, R3, R4, RN, L, V, X, a, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

MENIN INHIBITORS AND METHODS OF USE FOR TREATING CANCER

The present disclosure provides compounds represented by Formula (I), or a pharmaceutically acceptable salt thereof, wherein Ra, Rb, Rc, Rd, V, Q, T, n, p, q, r and s are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat cancer or any other disease, condition, or disorder that is responsive to inhibition of menin.

Farnesoid X receptor (FXR) stimulant

The invention belongs to the technical field of medicines, and particularly relates to a compound as shown in the formula (I), and pharmaceutically acceptable salt and ester or a stereisomer thereof.R1, R2, R3, R4, W, A, Z, E, X, Y and n are as defined in

COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE

The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

Novel kinase inhibitors

The present invention relates to a novel kinase inhibitor useful as a medicine for tumor, nerve disorder and mental illness. The purpose of the present invention is to provide a compound having improved blood-aqueous barrier penetrability to neurodegenerative diseases that cancer spreads to brain or progresses in brain. To this end, provided is a compound represented by chemical formula 1 or a pharmaceutically allowable salt thereof.COPYRIGHT KIPO 2017