198290-36-7

Upstream product

• 131511-13-2 4-(N-benzylamino)cyclohexanone ethylene acetal 
• 76-02-8 trifluoroacetyl chloride 

Downstream Products

• 198290-26-5 4-(N-benzyltrichloroacetamido)-1-cyclohexene 
• 226883-07-4 N-(cyclohex-3-enyl)-2,2,2-trichloroacetamide 
• 226883-03-0 trans-4-(N-benzyltrichloroacetamido)-1-cyclohexanol 
• 226883-04-1 4-(N-benzyltrichloroacetamido)-1-cyclohexyl methanesulfonate 
• 198290-29-8 N-Benzyl-2,2,2-trichloro-N-<4-(trimethylsilyloxy)cyclohex-3-enyl>acetamide 
• 198290-27-6 N-(4-Acetoxycyclohex-3-enyl)-N-benzyl-2,2,2-trichloroacetamide 
• 198290-25-4 4-(N-benzyltrichloroacetamido)-1-cyclohexanone 

Relevant academic research and scientific papers

A radical route to morphans. Synthesis and spectroscopic data of the 2- azabicyclo[3.3.1]Nonane

The synthesis of 1-benzyl-2-azabicyclo[3.3.1]nonan-3-one (8) through radical cyclization, involving an intramolecular addition of a carbamoyl- dichloromethyl radical upon an alkene, is described. Conversion of 8 to the morphan itself, and the spectroscopic analysis of some derivatives of this series are reported.

Cyclization of 1-(carbamoyl)dichloromethyl radicals upon activated alkenes. A new entry to 2-azabicyclo[3.3.1]nonanes

The synthesis of 2-azabicyclo[3.3.1]nonanes using a radical cyclization process as the piperidine ring-forming step is described. The reaction involves 1-(carbamoyl)dichloromethyl radicals which react intramolecularly with simple or activated alkenes, such as enol acetates or silyl enol ethers.