1983-27-3

Basic information

• Product Name: CHLOROMETHYLPHOSPHONOTHIOIC DICHLORIDE
• Synonyms: CHLOROMETHYLPHOSPHONOTHIOIC DICHLORIDE
• CAS NO: 1983-27-3
• Molecular Formula: CH₂Cl₃PS
• Molecular Weight: 183.42
• Mol File: 1983-27-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 89°C 30mm
• Flash Point: 89°C/30mm
• Appearance: /
• Density: 1.649g/cm³
• Vapor Pressure: 0.275mmHg at 25°C
• Refractive Index: 1.5750
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: CHLOROMETHYLPHOSPHONOTHIOIC DICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CHLOROMETHYLPHOSPHONOTHIOIC DICHLORIDE(1983-27-3)
• EPA Substance Registry System: CHLOROMETHYLPHOSPHONOTHIOIC DICHLORIDE(1983-27-3)

Safety Data

• Statements: 14-20/21/22-34
• Safety Statements: 26-36/37/39
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 1983-27-3(Hazardous Substances Data)

Usage

General Description

Chloromethylphosphonothioic dichloride is a chemical compound with the formula Cl2P(S)CH2Cl. It is a colorless to pale yellow liquid that is highly reactive and flammable. It is primarily used as an intermediate in the production of organophosphorus compounds and has applications in the synthesis of pesticides, herbicides, and flame retardants. It is also known to be a highly toxic substance that can cause severe respiratory irritation, eye and skin burns, and in high concentrations, it can be fatal if ingested or inhaled. Due to its hazardous properties, it is important to handle this compound with extreme caution and use appropriate safety measures when working with it.

InChI:InChI=1/CH2Cl3PS/c2-1-5(3,4)6/h1H2

Upstream product

• 1983-26-2 chloromethylphosphonic dichloride 
• 291-21-4 [1,3,5]trithiane 

Downstream Products

• 1071-83-6 N-(phosphonemethyl)glycine 
• 42585-01-3 C₁₁H₁₆ClN₂O₃PS 
• 42371-91-5 C₁₀H₁₄ClN₂O₃PS 
• 42371-93-7 C₁₀H₁₃Cl₂N₂O₃PS 
• 42585-05-7 C₁₀H₁₃Cl₂N₂O₃PS 
• 42585-14-8 C₁₁H₁₆Cl₂NOPS 
• 42585-09-1 C₁₁H₁₆Cl₂NOPS 
• 55560-31-1 C₁₁H₁₆ClN₂O₃PS 
• 42371-89-1 C₁₁H₁₆ClN₂O₃PS 
• 42585-02-4 C₁₀H₁₄ClN₂O₃PS 
• 2155-78-4 dichloro(chloromethyl)phosphine 
• 55560-34-4 O,O-Bis(2-chlor-4-nitrophenyl)(chlormethyl)phosphonothioat 
• 42585-06-8 C₁₁H₁₅Cl₂N₂O₃PS 
• 55560-32-2 C₁₁H₁₅Cl₂N₂O₃PS 

Relevant articles and documents

A “masked” source for the phosphaalkene MesP=CH2: Trapping, rearrangement, and oligomerization

We report the attempted synthesis of a “masked” phosphaalkene by treating MgA·3THF (A?=?anthracenide) with MesPCl(CH2Cl). Although the desired “masked” phosphaalkene could not be isolated, indirect evidence for its formation was obtained. The product of trapping MesP=CH2 with 1,3-cyclohexadiene was detected. In addition, the oxide MesPO(Me)A was isolated and crystallographically characterized from the MgA·3THF and MesPCl(CH2Cl) experiment described above. Finally, the attempted isolation of “masked” phoshaalkene afforded P-containing oligomers with a trimodal molecular weight distribution [Mn?=?640, 1.7?×?103 and 7.4?×?103?Da].

1,4,2-Diazaphospholothiazoles and -pyridines by a Hantzsch-Type Condensation Using Chloromethyldichlorophosphane

The cyclocondensation of 2-amino-1,3-thiazoline, 2-aminopyridines, 2- and 4-aminopyrimidines, 2-aminopyrazine, and 2-aminoquinoline with chloromethyldichlorophosphane in the presence of triethylamine yields regiospecifically 5,6-dihydrothiazolodiazaphosphole (3), 1,4,2-diazaphospholopyridines (12), 1,4,2-diazaphospholopyrimidines (15), 1,4,2-diazaphospholopyrimidine (17), 1,4,2-diazaphospholopyrazine (19), and diazaphospholoquinoline (22), respectively.Using 2-amino-1,3-thiazole (4) and 2-aminobenzothiazoles 8, we obtained mixtures of the 1,5- and 4,5-anellated 1,4,2-diazaphospholes 5/6, 9a/10a and 9b/10b, while in the case of the methyl derivative 8c only the diazaphospholobenzothiazole 10c was formed.In the reaction of 2-aminothiazole and 2-aminopyrazine with chloromethyldichlorophosphane the bis(diazaphospholo)-substituted chloromethylphosphanes 7 and 20 could be detected.The new anellated 1,4,2-diazaphospholes are colorless to pale yellow crystalline moisture-sensitive solids. - Key Words: Anellated azaphospholes/ Hantzsch-type cyclocondensation/ Chloromethyldichlorophosphane/ Regioselectivity/ 31P-, 1H-, 13-C-NMR spectra

REACTION OF PHOSPHORUS TRICHLORIDE WITH s-TRITHIANE (TRITHIOFORMALDEHYDE)

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