19832-87-2

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5-methyl-1,4-benzoquinone is used as a reactant in the synthesis of benzofuran-5-ols, which possess antifungal activity. These synthesized compounds can be employed as active ingredients in the development of antifungal medications, targeting a wide range of fungal infections.
Used in Chemical Synthesis:
In the field of organic chemistry, 2-chloro-5-methyl-1,4-benzoquinone can be utilized as a key intermediate in the synthesis of various complex organic molecules. Its unique structural features make it a valuable building block for creating novel compounds with potential applications in different industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
Due to its reactivity and structural properties, 2-chloro-5-methyl-1,4-benzoquinone can be a valuable compound for research and development purposes. It can be used in the design and synthesis of new molecules with specific biological activities or material properties, contributing to the advancement of scientific knowledge and the development of innovative products.

Upstream product

• 64-17-5 ethanol 
• 16906-55-1 5,6-dichloro-2-methyl-cyclohex-2-ene-1,4-dione 
• 77019-79-5 2-chloro-6-methyl-p-phenylenediamine 
• 553-97-9 2-Methyl-1,4-benzoquinone 
• 7664-93-9 sulfuric acid 
• 5307-03-9 2-chloro-5-methyl-1,4-phenylenediamine 
• 108-39-4 3-methyl-phenol 
• 95-79-4 5-chloro-2-methyl-benzenamine 
• 89-60-1 1-chloro-4-methyl-2-nitro-benzene 
• 861619-80-9 5-chloro-2-methyl-4-nitroso-phenol 
• 5306-98-9 5-chloro-2-methyl-phenol 
• 344794-49-6 2-chloro-4-methoxy-5-methyl-aniline 
• 6971-38-6 p-nitroso-o-cresol 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 5465-62-3 2-chloro-5-methyl-hydroquinone 
• 157824-94-7 2,3-Dichloro-5-methylbenzene-1,4-diol 
• 187809-42-3 3-bromo-2-chloro-5-methyl-hydroquinone 
• 98507-22-3 2-Chloro-N,N'-dicyano-5-methyl-1,4-benzoquinonediimine 
• 129247-31-0 1,2,7-Trimethyl-3-ethoxycarbonyl-4-chloro-5-hydroxyindole 
• 129247-35-4 2-Chloro-3-(β-methylamino-β-methyl-α-ethoxycabonl)vinyl-5-methylbenzoquinone 
• 129247-33-2 2-Chloro-3-(β-methylamino-β-methyl-α-ethoxycarbonyl)vinyl-5-methylhydroquinone 
• 129247-32-1 1-Ethyl-2,7-dimethyl-3-ethoxycarbonyl-4-chloro-5-hydroxyindole 
• 129247-34-3 2-Chloro-3-(β-ethylamino-β-methyl-α-ethoxycarbonyl)vinyl-5-methylhydroquinone 
• 129247-38-7 2-Chloro-3-(β-benzylamino-β-methyl-α-ethoxycarbonyl)vinyl-5-methylhydroquinone 
• 4592-97-6 2,3,5-trichloro-6-methyl-1,4-benzoquinone 
• 57982-80-6 2-chloro-5-methyl-[1,4]benzoquinone-4-oxime 

Relevant academic research and scientific papers

Oxidation of phenols with chlorine dioxide

The oxidation of different phenols, viz., phenol, 3-methylphenol, 4-methylphenol, 4-tert-butylphenol, 2-cyclohexylphenol, 2,6-di-tert-butyl-4- methylphenol, and 2,4-dichlorophenol, with chlorine dioxide in acetonitrile was studied spectrophotometrically. The reaction rate is described by a second-order equation w = k[PhOH]? [ClO2]. The rate constants were measured and activation parameters of oxidation were determined in a temperature interval of 10-60°C. A dependence of the reaction rate constant on the phenol structure was found. The oxidation products were identified, and their yields were established.

Ultrasonically activated oxidation of hydroquinones to quinones catalysed by ceric ammonium nitrate doped on metal exchanged K-10 clay

We have accomplished the oxidation of hydroquinones to quinones in quantitative yields using catalytic quantity of ceric ammonium nitrate doped on various metal-exchanged K-10 clay, as a mild and efficient reagent, by ultrasonic activation. The exchanged cations examined were Fe3+, Cu2+, Ce4+ and K-10 clay itself. The best results were obtained using Fe3+-Mont. K-10 clay.

Chlorination of quinonoid compounds using dichlorine monoxide

Dichlorine monoxide is a selective reagent for the monochlorination at the active quinonoid position in benzoquinones and naphthoquinones.

Selective halogenation of 1,4-benzoquinones and 1,4-naphthoquinones with copper(II) halide adsorbed on alumina

1,4-Benzoquinone or 1,4-naphthoquinone and their derivatives have been halogenated selectively at quinonoid positions with copper(II) halide adsorbed on neutral alumina followed by refluxing in halobenzene to give mono-, di-, tri- and tetra-haloquinones.